Evaluation of Corneal Optic Quality in Amblyopia

Objective: To compare corneal aberrations and densitometry values in children with amblyopia due to anisometropic hyperopia with those of healthy children. Methods: This study included 173 children with amblyopia due to hyperopic anisometropia in one eye and 173 children with both healthy eyes. The amblyopic eye (Group 1) and the fellow normal eye (Group 2) of the amblyopic patients and the right eye of the healthy control group (Group 3) were evaluated. Of the corneal aberration and corneal densitometry (CD) measured using Scheimpflug corneal topography values were noted. Results: While there was a significant difference in total root mean square (RMS), higher-order aberration (HOA) RMS, coma horizontal, trefoil horizontal and spherical aberration values between the groups (p

Ambliyopide Korneal Optik Kalitenin Değerlendirilmesi

Amaç: Anizometropik hipermetropiye bağlı ambliyopili çocuklarda korneal aberasyonları ve dansitometri değerlerini sağlıklı çocuklarla karşılaştırmak. Yöntemler: Bu çalışmaya bir gözünde hipermetropik anizometropiye bağlı ambliyopi olan 173 çocuk ve her iki gözü sağlıklı 173 çocuk dahil edildi. Ambliyopik hastaların ambliyopik gözü (Grup 1), diğer normal gözü (Grup 2) ve sağlıklı kontrol grubunun sağ gözü (Grup 3) değerlendirildi. Scheimpflug korneal topografi kullanılarak ölçülen korneal aberasyon ve korneal dansitometri değerleri not edildi. Sonuçlar: Gruplar arasında toplam kök ortalama kare, yüksek dereceli aberasyon kök ortalama kare, koma yatay, trefoil yatay ve sferik aberasyon değerlerinde anlamlı farklılık varken (p

___

1. Barrett BT, Bradley A, McGraw PV. Understanding the neural basis of amblyopia. Neuroscientist. 2004; 10: 106-17.

2. Carlton J, Kaltenthaler E. Amblyopia and quality of life: a systematic review. Eye (Lond). 2011; 25: 403- 13.

3. Multi-ethnic Pediatric Eye Disease Study Group. Prevalence of amblyopia and strabismus in African American and Hispanic children ages 6 to 72 months the multi-ethnic pediatric eye disease study. Ophthalmology. 2008; 115: 1229-36.e1.

4. Wallace DK, Morse CL, Melia M, et al. Pediatric eye evaluations preferred practice pattern®. American academy of pediatric ophthalmology/strabismus preferred practice pattern pediatric ophthalmology panel. Ophthalmology. 2018; 125: 184-227.

5. Cho YK, Chang HS, La TY, et al. Anterior segment parameters using Pentacam and prediction of corneal endothelial cell loss after cataract surgery. Korean J Ophthalmol. 2010; 24: 284-90.

6. Otri AM, Fares U, Al-Aqaba MA, Dua HS. Corneal densitometry as an indicator of corneal health. Ophthalmology. 2012; 119: 501-8.

7. Lee SH, Chang JW. The relationship between higher-order aberrations and amblyopia treatment in hyperopic anisometropic amblyopia. Korean J Ophthalmol. 2014; 28: 66-75.

8. Kirwan C, O’Keefe M. Association between amblyopia and HOAs. J Cataract Refract Surg. 2007; 33: 1833-5.

9. Dhubhghaill SN, Rozema JJ, Jongenelen S, et al. Normative values for corneal densitometry analysis by Scheimpflug optical assessment. Invest Ophthalmol Vis Sci. 2014; 55: 162-8.

10. Meek KM, Leonard DW, Connon CJ, Dennis S, Khan S. Transparency, swelling and scarring in the corneal stroma. Eye (Lond). 2003; 17: 927-36.

11. Kling S, Hafezi F. Corneal biomechanics - a review. Ophthalmic Physiol Opt. 2017; 37: 240-52.

12. Daxer A, Misof K, Grabner B, Ettl A, Fratzl P. Collagen fibrils in the human corneal stroma: structure and aging. Invest Ophthalmol Vis Sci. 1998; 39: 644-8.

13. McAlinden C, Khadka J, Pesudovs K. A comprehensive evaluation of the precision (repeatability and reproducibility) of the Oculus Pentacam HR. Invest Ophthalmol Vis Sci. 2011; 52: 7731-7.

14. Plech AR, Pinero DP, Laria C, Aleson A, Alio JL. Corneal higher-order aberrations in amblyopia. Eur J Ophthalmol. 2010; 20: 12-20.

15. Applegate RA, Thibos LN, Hilmantel G. Optics of aberroscopy and super vision. J Cataract refract Surg. 2001; 27: 1093-107.

16. Kızıltoprak H, Koç M, Tekin K, et al. Evaluation of high-order corneal aberrations in children with well controlled type 1 diabetes mellitus. Dicle Med J. 2018; 45: 71-5.

17. Coşkun M, Doğan H, Öner AÖ. The effectiveness of occlusion treatment on anisometric amblyopia in different age groups. Dicle Med J. 2009; 36: 28-34.

18. Patel S, McLaren JW, Hodge DO, Bourne VM. The effect of corneal light scatter on vision after penetrating keratoplasty. Am J Ophthalmol. 2008; 146: 913–9.

19. Niederer RL, Perumal D, Sherwin T, McGhee CNJ. Age-related diferences in the normal human cornea: a laser scanning in vivo confocal microscopy study. Br J Ophthalmol. 2007; 91: 1165-9.

20. Cankaya AB, Tekin K, Kiziltoprak H, Karahan S, Yilmazbas P. Assessment of corneal backward light scattering in the healthy cornea and factors affecting corneal transparency. Jpn J Ophthalmol. 2018; 62: 335-41.

21. Garzón N, Poyales F, Illarramendi I, et al. Corneal densitometry and its correlation with age, pachymetry, corneal curvature, and refraction. Int Ophthalmol. 2017; 37: 1263-8.

22. Boote C, Dennis S, Newton RH, Puri H, Meek KM. Collagen fibrils appear more closely packed in the prepupillary cornea: optical and biomechanical implications. Invest Ophthalmol Vis Sci. 2003; 44: 2941-8.

23. O’Donnell C, Wolffsohn JS. Grading of corneal transparency. Cont Lens Anterior Eye. 2004; 27: 161-70.

24. Hayes S, Boote C, Lewis J, et al. Comparative study of fibrillar collagen arrangement in the corneas of primates and other mammals. Anat Rec (Hoboken). 2007; 290: 1542-50.
Dicle Tıp Dergisi-Cover
  • ISSN: 1300-2945
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1963
  • Yayıncı: Cahfer GÜLOĞLU
Sayıdaki Diğer Makaleler

The reasons for conversion from laparoscopic appendectomy to open surgery in children: the first experience on 100 cases in a single center

Ali Erdal KARAKAYA

Çocuklarda Laparoskopik Apendektomiden Açık Cerrahiye Geçiş Nedenleri: İlk 100 Vaka Deneyimİ

Ahmet Gökhan GÜLER, Mehmet Fatih YAZAR, Ali Erdal KARAKAYA, Ahmet Burak DOĞAN

Management of Adults With Suspected Foreign Body Aspiration

Efsun UĞUR, Elif TANRIVERDİ, Demet TURAN, Binnaz YILDIRIM, Şeyma YILMAZ, İrfan CHOUSEİN, Mehmet Akif ÖZGÜL, Erdoğan ÇETİNKAYA

Peripheral Silent Period In Cervical and Generalized Dystonia

Melih TÜTÜNCÜ, Hikmat ABBASZADE, Ayşegül GÜNDÜZ, Meral E. KIZILTAN

Kronik Otitis Media’da Tiyol-Disülfid Homeostazının Değişikliği

Muhammed AYRAL, Serdar Ferit TOPRAK, Serkan DEDEOĞLU, İlhan SABANCILAR, Hakan TEMİZ

İleri Evre Medüller Tiroid Kanseri Tedavisinde Tirozin Kinaz İnhibitörü Kullanımı-Tek Merkez Deneyimi

Senar EBINC, Zeynep ORUÇ, Zuhat URAKÇI, Muhammet Ali KAPLAN, Mehmet KÜÇÜKÖNER, Abdurrahman IŞIKDOĞAN

Akut Koroner Sendrom Hastalarında Syntax Skoru İle Epikardiyal Yağ Doku Arasındaki İlişki

Adem ATICI, Fatih ÖZTÜRK, Yunus Emre OKUDAN, Ali Yaşar KILINÇ, Mehmet YAMAN, Hakkı ŞİMŞEK, Koray DEMİR, Serkan AKDAĞ

Servikal ve Jeneralize Distonide Periferik Sessiz Periyot

Melih TÜTÜNCÜ, Hikmat ABBASZADE, Ayşegül GÜNDÜZ, Meral E. KIZILTAN

Optimal Tedavi, Altmış Beş Yaş ve Üstü Glioblastome Multiforme Tanılı Hastalarda Sağkalım Üzerine Etkili mi?

Atike Gökçen DEMİRAY, Arzu YAREN, Burcu YAPAR TASKÖYLÜ, Serkan DEĞİRMENCİOĞLU, Gamze GÖKÖZ DOĞU

Evaluation Of Tumoral Lesions Of The Skin And Subcutaneous Tissue Of The Head And Neck In Geriatric Population

Kemal Koray BAL, Talih ÖZDAŞ, Emin KAPI, Sedat ALAGÖZ, Elif Burcu ŞENYURT, Asiye Merve ERDOĞAN, Ragıp Onur ÖZTORNACI