Derin Boyun Enfeksiyonlu Hastalarda Nötrofil/ Lenfosit Oranının Prognozla İlişkisi

Amaç: Bu çalışmanın amacı, derin boyun enfeksiyonu olan hastaların nötrofil/lenfosit oranıyla prognozları ara- sında bir ilişki olup olmadığını göstermektir. Yöntemler: Çalışmada Ocak 2010 ile Ocak 2015 yılla- rı arasında Dicle Üniversitesi Tıp Fakültesi Kulak Burun Boğaz ve Baş boyun Cerrahisi Kliniği’nde derin boyun enfeksiyonu tanısı alarak yatırılan ve tedavi edilen 108 hasta değerlendirildi. Hastaların demografik özellikleri, klinik dataları, komplikasyonları ve tedavi sonuçları ince- lendi. Çalışmaya, 0-14 yaş aralığındaki pediatrik hastalar, sadece peritonsiller apsesi olanlar ve travmaya sekonder gelişmiş enfeksiyonu olanlar dahil edilmedi. Derin boyun enfeksiyonlu hastalar, takip ve tedavileri esnasında haya- tı tehdit edici komplikasyon gelişen (2. grup) ve gelişme- yenler (1.grup) olarak iki ana gruba ayrıldı. Bulgular: Derin boyun enfeksiyonlu hastalarımızın 14 (%13) ’ünde yaşamı tehdit edici komplikasyonlar gelişir- ken, 94 (%87) hastamızın ise tedavi ve takipleri esnasın- da herhangi bir ciddi komplikasyona rastlanmadı. Kompli- kasyon gelişen hastalarda ortalama nötrofil/lenfosit oranı komplikasyon gelişmeyen hastalara göre istatistiki olarak anlamlı yüksek bulundu (p

Relationship between Neutrophil-to-Lymphocyte Ratio and Prognosis in Patients with Deep Neck Space Infection

Objective: The aim of this study was to demonstrate if there is any relation between the neutrophil-to-lympho- cyte ratio and prognosis in patients with deep neck space infections Methods: One hundred eight patients who were interned and treated due to deep neck infection in department of otolaryngology between January 2010 and January 2015 were analyzed. Demographics, clinical data, complica- tions and treatment results of patients were evaluated. Pe- diatric patients between the age of 0 and 14, the patients who had only peritonsillary abscess, infection secondary to trauma were excluded from study. During follow-up and treatment duration the patients with deep neck infections were divided into two groups according to whether they had any complication (group 1) or not (group 2). Results: Fourteen (13%) patients with deep neck in- fections had life-threatening complications whereas 94 (87%) did not have any complication during follow-up and treatment duration. The mean neutrophil-to-lymphocyte ratio in patients with complications was significantly high- er than the patients without any complications (p<0.05). Also a statistically significant difference was found in advanced age and mean neutrophil value evaluation (p <0.05). However there was no significant difference in mean lymphocyte value (p >0.05). Conclusion: This study showed that the neutrophil-to- lymphocyte ratio can be used as a cheap, easily obtained and predictive prognostic factor in patients with deep neck infections.

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  • 1. Huang TT, Liu TC, Chen PR, et al. Deep neck infection: analysis of 185 cases. Head Neck 2004;26:854-860.
  • 2. Boscolo-Rizzo P, Stellin M, Muzzi E, et al. Deep neck infec- tions: a study of 365 cases highlighting recommendations for management and treatment. Eur Arch Otorhinolaryngol 2012;269:1241-1249.
  • 3. Yang SW, Lee MH, Lee YS, et al. Analysis of life-threat- ening complications of deep neck abscess and the impact of empiric antibiotics. ORL J Otorhinolaryngol Relat Spec 2008;70:249-256.
  • 4. A. Mantovani, M.A. Cassatella, C. Costantini, S. Jaillon. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011;11:519-531.
  • 5. B. Amulic, C. Cazalet, GL. Hayes, et al. Neutrophil func- tion: from mechanisms to disease. Ann Rev Immunol 2012;30:459-489.
  • 6. Nunez J, Nunez E, Bodi V, et al. Usefulness of the neutrophil to lymphocyte ratio in predicting long-term mortality in ST segment elevation myocardial infarction. Am J Cardiol 2008;101:747-752.
  • 7. Walsh SR, Cook EJ, Goulder F, et al. Neutrophil lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg On- col 2005;91:181-184.
  • 8. Baglam T, Binnetoglu A, Yumusakhuylu AC, et al. Predictive value of the neutrophil-to-lymphocyte ratio in patients with deep neck space infection secondary to acute bacterial ton- sillitis. Int J Pediatr Otorhinolaryngol 2015;79:1421-1424.
  • 9. S. Ulu, M. S. Ulu, A. Bucak, et al. Neutrophil-to-lymphocyte ratio as a new, quick,and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss. Otology & Neurotology 2013;34:1400-1404.
  • 10. İlhan M, İlhan G, Gök AF, et al. Evaluation of neutrophil- lymphocyte ratio, platelet-lymphocyte ratio and red blood cell distribution width-platelet ratio as early predictor of acute pancreatitis in pregnancy. J Matern Fetal Neonatal Med 2015;5:1-5.
  • 11. Unal D, Eroglu C, Kurtul N, et al. Are neutrophil/lympho- cyte and platelet/lymphocyte rates in patients with non- small cell lung cancer associated with treatment response and prognosis? Asian Pac J Cancer Prev 2013;14:5237- 5242.
  • 12. Rudiger A, Burckhardt OA, Harpes P, et al. The relative lymphocyte count on hospital admission is a risk factor for long-term mortality in patients with acute heart failure. Am J Emerg Med 2006;24:451-454.
  • 13. Yilmaz B, Sengül E, Gül A, et al. Neutrophil–lymphocyte ratio as a prognostic factor in laryngeal carcinoma. Indian J Otolaryngol Head Neck Surg. DOI 10.1007/s12070-014- 0769-4.
Dicle Tıp Dergisi-Cover
  • ISSN: 1300-2945
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1963
  • Yayıncı: Cahfer GÜLOĞLU
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