Seval ERPOLAT, Zehra ARSLANYILMAZ, İkbal KAYGUSUZ

Akne Vulgarisli Hastalarda Serum Çinko Düzeyleri ve Akne Şiddetiyle Korelasyonu

Amaç: Akne vulgaris adölesan ve genç erişkinleri etkileyen en yaygın deri hastalığıdır. Çinko insanlar için esansiyel bir elementtir. Bazı çalışmalarda serum çinko seviyeleri ve akne vulgaris arasında bir ilişki raporlanmıştır. Bu çalışmamızın amacı akne vulgarisli hastalarda serum çinko düzeyini ölçmek ve bunun akne şiddetiyle korelasyonunu değerlendirmektir.Yöntemler: 43 akne vulgaris hastası ve 37 sağlıklı gönüllü çalışmaya alındı. Hasta grubunda Global Akne Derecelendirme Sistemine (GADS) göre akne şiddeti belirlendi. Serum Çinko düzeyleri hasta ve kontrol grubunda ölçüldü.Bulgular: Aknesi olan hastalarda çinko düzeyi 81.48 ± 14.21 µg/dl, kontrol grubunda 83,69 ± 12,43 µg/dl olarak tespit edildi, çinko düzeyi açısından gruplar arasında istatistiksel olarak anlamlı bir farklılık izlenmedi (p=0,46). Aknesi olan hastaların akne şiddeti ile çinko düzeyleri arasında negatif korelasyon tespit edildi ama istatistiksel olarak anlamlılık izlenmedi (r=-0,024, p=0,88)Sonuç: Bizim sonuçlarımız serum çinko düzeyleri ile akne şiddeti arasında herhangi bir ilişki olmadığını göstermektedir. Daha ileri çalışmalar gerekmektedir.

Serum Zinc Levels in Patients with Acne Vulgaris and Its Correlation with Severity of Acne

Objective: Acne vulgaris the most common cutaneous disorder affecting adolescent and young adults. Zinc is an essential element for human. We aimed to evaluate the serum zinc level in patients with acne vulgaris and correlate with the severity of disease.Methods: The study included 43 patients with acne vulgaris and 37 healthy control subjects. The severity of acne was assessed according to Global Acne Grading System. The serum zinc levels were measured both patients and control subjects.Results: The serum zinc level in acne patients were 81.48 ± 14.21 µg/dl and 83.69 ± 12.43 µg/dl in control subjects. There was no statistically significant difference between patients and control subjects (p=0.46).There was a negative correlation between acne severity and serum zinc levels but there was no statistically significant (r=-0.024, p=0.88).Conclusion: The results of our study revealed no relation between serum zinc levels and acne. Further studies are needed.

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