Ertuğrul Emre GÜNTÜRK, Selçuk DOĞAN, Ayşe Nur TOPUZ

Premenapozal migren hastalarında aort sertliği parametrelerinin değerlendirilmesi

Amaç: Migren, ağırlıklı olarak kadınlar olmak üzere yetişkin nüfusun yaklaşık %10’unu etkileyen epizodik birincil baş ağrısı bozukluğudur. Migrende tespit edilen değişikliklere ve önceki bulgulara dayanarak, arteriyel sertliğin migren hastalarında vasküler olaylara önemli bir katkıda bulunduğu düşünülebilir. Bu çalışmanın amacı, premenapozal migren hastalarında aort sertliğinin değerlendirilmesi ile ateroskleroz ve migren arasındaki ilişkiyi araştırmaktır.Gereç ve Yöntem: Çalışmaya migreni olan 68 premenapozal kadın hasta ve 39 sağlıklı kadın kontrol grubu olarak dahil edildi. Migren ve arteriyel sertlik arasındaki ilişkiyi ortaya çıkarmak için tüm katılımcılara ekokardiyografi uygulandı ve aort sertlikleri değerlendirildi. Katılımcıların kan basıncı ölçümleri, temel biyokimyasal testleri ve 12 derivasyon EKG kayıtları eşzamanlı alındı. Bulgular: Temel ekokardiyografik bulgular hasta ve kontrol grubunda benzerdi. Aortun sistolik ve diastolik çapları, aort çapındaki değişim oranları her iki grupta benzerdi. Auralı ve aurasız migrenli hastalar ve kontrol grupları arasında sistolik, diastolik ve nabız basınçları açısından anlamlı farklılık tespit edilmedi. Sonuç: Aterosklerozun bir belirteci olarak aort sertliği parametreleri Migren hastaları ile kontrol grubu arasında farklı değildir.

Anahtar Kelimeler:

Migraine, Arterial stiffness

Evaluation of aortic stiffness parameters in premenopausal migraine patients

Purpose: Migraine is an episodic primary headache disorder, which affects approximately 10% of the adult population, predominantly females. Based on the changes detected in migraine and previous findings, arterial stiffness can be considered to be an important contributor to vascular events in patients with migraine. The aim of this study was to investigate the associations between atherosclerosis and migraine through the evaluation of aortic stiffness in premenopausal migraine patients.Materials and Methods: The study included 68 female patients with migraine, and a control group of 39 healthy females. To reveal the association between migraine and arterial stiffness, echocardiography was applied and aortic stiffness was evaluated. Blood pressure measurements, basic biochemical tests and the 12 derivation-ECG recordings of each patient were taken simultaneously. Results: Basic echocardiographic findings were similar in patients and the control group. Systolic and diastolic diameters of the aorta, and the change in aortic diameter were also similar in both groups. Aortic distensibility, aortic strain and beta indices were also similar in both groups. No significant differences were determined between patients with and without aura migraine and the control group in respect of systolic blood pressure, diastolic blood pressure and pulse pressure. Conclusion: As a marker of atherosclerosis, the aortic stiffness parameters didn’t differ between migraine and control group.

Keywords:

Migraine, arterial stiffness,

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