Burak METE, Mehmet Sait DEĞER, Gülsüm ZOROĞLU

Kan lipitleri, inflamasyon belirteçleri ve vücut kompozisyonu arasındaki ilişki

Amaç: Bu çalışma ile inflamasyon belirteçleri ile antropometrik ölçüm değerleri ve kan lipit değerleri arasındaki ilişkinin tespit edilmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışma 2019 yılında 274 yetişkin sağlıklı kişi üstünde yapılmış bir çalışmadır. Kişilerin kan lipit değerleri, tam kan sayımı inflamasyon belirteçleri nötrofil lenfosit oranı (NLO), platelet lenfosit oranı (PLO) ve lenfosit monosit oranı (LMO) ile antropometrik ölçümleri arasındaki ilişki incelenmiştir. Bulgular: Çalışmaya katılan 274 kişinin yaş ortalaması 34’dür. BKİ’ne göre NLO, PLO ve LMO oranları arasında anlamlı fark bulunamamıştır. PLO ile iskelet kası, bazal metabolik hız, vücut sıvı miktarı ve yağsız kütle arasında anlamlı çok zayıf negatif korelasyon, HDL ile BMİ, vücut yağ miktarı, iç yağlanma miktarı arasında zayıf negatif yönde korelasyon bulunmuştur. İskelet kası ve vücut yağ miktarındaki artış total kolesterol seviyesinde azalışa neden olurken, iç yağlanma miktarındaki artış total kolesterol seviyesinde artışa neden olmaktadır. NLO ile LDL arasında pozitif yönde zayıf, NLO ile total kolesterol arasında pozitif yönde çok zayıf, LMO ile LDL arasında pozitif yönde çok zayıf korelasyon bulunmuştur. Sonuç: Antropometrik değerler ile inflamasyon belirteçleri arasında çok zayıf, kan lipit ile zayıf-orta düzey, inflamasyon belirteçleri ile kolesterol düzeyi arasında zayıf ilişki olduğu görülmüştür.

Anahtar Kelimeler:

inflamasyon mediyatörleri, vücut kitle indeksi, kolesterol, nötrofiller

Relationship between blood lipids, inflammation parameters and body composition

Purpose: The aim of this stuıdy was to determine the relation between inflammation markers, anthropometric measurements, and blood lipid values. Materials and Methods: The present study was conducted with 274 adult healthy subjects in 2019. The relationship between anthropometric measurements and blood lipid values of individuals, full blood count inflammation markers, neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) and lymphocyte monocyte ratio (LMR) were examined.. Results: The average age of the 274 subjects, who participated in the study, was 34 years. No significant differences were detected between the NLR, PLR and LMR ratios according to the BMI scores. A very weak and negative correlation was detected between PLR and skeletal muscle, basal metabolic rate, body fluid amount and lean mass; and a weak and negative correlation was detected between HDL and BMI, body fat amount, and internal fat amount. A weak and positive correlation was detected between NLR and LDL. Conclusion: There was a very weak correlation between anthropometric values and inflammation markers, a weak-moderate correlation between blood lipid levels, and a weak correlation between inflammation markers and cholesterol levels.

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