Mustafa ULUBAY, Uğur KESKİN, Ulaş FİDAN, Fahri FIRATLIGİL, Rıza KARACA, Mustafa ÖZTÜRK, İbrahim EKER, İbrahim ALANBAY, Ali ERGÜN

Hematopoetik Kök Hücre Transplantasyonu İle Tetiklenen Ovaryan Yetmezliğe Bağlı Gelişen Labial Adezyon

Labial adezyon, labium major ve / veya minör lerin tamamen veya kısmi birleşmesi sonrası oluşan bir hastalıktır. Genellikle arka forşette gelişir ve bazen de üretra ağzına ve klitorise kadar uzanım gösterebilir. Labial adezyon daha çok puberte öncesi kız çocuklarında görülürken, 13-23 aylık yaş gurubunda pik yapar. Labial adezyona sebep olan faktörler bilinmemektedir. Hipoöstrojene bağlı gelişebilen vajinal irritasyon veya inflamasyon bu duruma sebep olabilecek hipotez olarak düşünülmektedir. Bu olguda hematopoetik kök hücre transplantasyonu sonrası gelişen ovaryan yetmezliğe bağlı gelişen labial adezyon sunuldu.

Ovarian Failure Induced Labial Adhesion after Hematopoietic Stem Cell Transplantation

Labial adhesion is a disease which occurs after complete or partial fusion of labium majors and / or minors. It usually originates at the posterior fourchette and sometimes progresses towards urethral opening and clitoris. Incidence of labial adhesion is most frequent in prepubescent girls with a peak incidence at the age of 13 – 23 months. The factors that cause labial adhesion remain unknown. Vaginal irritation or inflammation process with underlying hypoestrogenism can cause this disease.We present a case who developed labial adhesion due to ovarian failure after hematopoietic stem cell transplantation.

Keywords:

labial adhesion, hematopoietic stem cell transplantation, hypoestrogenism,

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