Bipolar bozukluk ve şizofrenide anksiyete duyarlılığı

Amaç: Bu çalışmada bipolar bozukluk ve şizofreni tanılı hastaların klinik ve sosyodemografik özelliklerinin anksiyete duyarlılığı ile ilişkisi incelenmiştir.

Anxiety sensitivity in bipolar disorder and schizophrenia

Purpose: This study investigated the relationship between the clinical and sociodemographic characteristics of patients with bipolar disorder and schizophrenia and the levels of anxiety sensitivity.Materials and Methods: Fifty-nine patients (33 females, 26 males) with bipolar disorder in the euthymic period without any comorbid mental disorders between the ages of 18-65 and 65 (28 females, 37 males) clinically stable patients with schizophrenia, and 88 (47 females, 41 males) healthy volunteer consist the sample group of the study. Young Mania Rating Scale (YMRS), Hamilton Depression Rating Scale (HDRS) were applied for patients with bipolar disorder, Positive and Negative Syndrome Scale (PANSS) for patients with schizophrenia and Anxiety Sensitivity Index-3 (ASI-3) to the whole sample group.Results: ASI-3 total, cognitive, and social subscale scores were significantly higher in patients with bipolar disorder and schizophrenia compared to the control group. Patients with bipolar disorder who had previous suicide attempts had significantly higher ASI-3 physical and total scores than those who did not attempt suicide. There was a significant linear correlation between physical, cognitive, and total scores of ASI-3 and PANSS positive scores of patients with schizophrenia.Conclusion: Anxiety sensitivity is higher in patients diagnosed with bipolar disorder and schizophrenia compared to healthy individuals. This study revealed that anxiety sensitivity is a predictor of previous suicide attempts in bipolar disorder, and in schizophrenia, it is associated with disorder severity, particularly with positive psychotic symptoms.

___

  • 1. Reiss S, McNally RJ. Expectancy model of fear. Theoretical issues in behavior therapy inside (Eds S. Reiss, RR Bootzin):107-21. San Diego, CA, Academic Press. 1985.
  • 2. Reiss S. Expectancy model of fear, anxiety, and panic. Clin Psychol Rev. 1991;11:141-53.
  • 3. Taylor S. Anxiety sensitivity: Theory, research, and treatment of the fear of anxiety (Ed IBWeiner) Routledge, 2014.
  • 4. Waszczuk MA, Zavos HMS, Antonova E, Haworth CM, Plomin R, Eley TC. A multivariate twin study of trait mindfulness, depressive symptoms, and anxiety sensitivity. Depress Anxiety. 2015;32:254-61.
  • 5. Gratz KL, Tull MT, Gunderson JG. Preliminary data on the relationship between anxiety sensitivity and borderline personality disorder: The role of experiential avoidance. J Psychiatr Res. 2008;42:550- 9.
  • 6. Mantar A, Yemez B, Alkın T. Anksiyete duyarlılığı indeksi-3’ün Türkçe formunun geçerlik ve güvenilirlik çalışması. Türk Psikiyatr Derg]. 2010;21:1-11.
  • 7. Keough ME, Riccardi CJ, Timpano KR, Mitchell MA, Schmidt NB. Anxiety symptomatology: The association with distress tolerance and anxiety sensitivity. Behav Ther. 2010;41:567-74.
  • 8. Schmidt NB, Zvolensky MJ, Maner JK. Anxiety sensitivity: Prospective prediction of panic attacks and Axis I pathology. J Psychiatr Res. 2006;40:691-9.
  • 9. Stewart SH, Peterson JB, Pihl RO. Anxiety sensitivity and self-reported alcohol consumption rates in university women. J Anxiety Disord. 1995;9:283-92.
  • 10. Timpano KR, Buckner JD, Richey JA, Murphy DL, Schmidt NB. Exploration of anxiety sensitivity and distress tolerance as vulnerability factors for hoarding behaviors. Depress Anxiety. 2009;26:343-53.
  • 11. Janke EA, Jones E, Hopkins CM, Ruggieri M, Hruska A. Catastrophizing and anxiety sensitivity mediate the relationship between persistent pain and emotional eating. Appetite. 2016;103:64-71.
  • 12. Capron DW, Blumenthal H, Medley AN, Lewis S, Feldner MT, Zvolensky MJ et al. Anxiety sensitivity cognitive concerns predict suicidality among smokers. J Affect Disord. 2012;138:239-46.
  • 13. Olatunji BO, Wolitzky-Taylor KB. Anxiety sensitivity and the anxiety disorders: a meta-analytic review and synthesis. Psychol Bull. 2009;135:974-99.
  • 14. Rifkin LS, Beard C, Hsu KJ, Garner L, Björgvinsson T. Psychometric properties of the anxiety sensitivity index-3 in an acute and heterogeneous treatment sample. J Anxiety Disord. 2015;36:99-102.
  • 15. Olthuis JV, Watt MC, Stewart SH. Anxiety Sensitivity Index (ASI-3) subscales predict unique variance in anxiety and depressive symptoms. J Anxiety Disord. 2014;28:115-24.
  • 16. Simon NM, Smoller JW, Fava M, Sachs G, Racette SR, Perlis R et al. Comparing anxiety disorders and anxiety-related traits in bipolar disorder and unipolar depression. J Psychiatr Res. 2003;37:187-92.
  • 17. Simon NM, Otto MW, Fischmann D, Racette S, Nierenberg AA, Pollack MH et al. Panic disorder and bipolar disorder: Anxiety sensitivity as a potential mediator of panic during manic states. J Affect Disord. 2005;87:101-5.
  • 18. Luzón O, Harrop C, Nolan F. Cognitive processes during acute psychosis: the role of heightened responsibility and catastrophic misinterpretations. Behav Cogn Psychother. 2009;37:357-77.
  • 19. Blanchard JJ, Andrea A, Orth RD, Savage C, Bennett ME. Sleep disturbance and sleep-related impairment in psychotic disorders are related to both positive and negative symptoms. Psychiatry Res. 2020;286:112857.
  • 20. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Washington DC, American Psychiatric Assocation, 2013.
  • 21. Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 1978;133:429-35.
  • 22. Karadağ F, Oral ET, Aran Yalçın F, Erten E. Young mani derecelendirme ölçeğinin Türkiye’de geçerlik ve güvenilirliği. Turk Psikiyatr Derg. 2001;13:107-14.
  • 23. Zimmerman M, Martinez JH, Young D, Chelminski I, Dalrymple K. Severity classification on the Hamilton depression rating scale. J Affect Disord. 2013;150:384-8.
  • 24. Akdemir A, Örsel S, Dağ İ, Türkçapar H, İşcan N, Özbay H. Hamilton Depresyon Derecelendirme Ölçeği (HDDÖ)’nin geçerliği, güvenirliği ve klinikte kullanımı. Psikiyatr Psikoloji Psikofarmakol Dergisi. 1996;4:251-9.
  • 25. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261-76.
  • 26. Leucht S, Kane JM, Kissling W, Hamann J, Etschel E, Engel RR. What does the PANSS mean? Schizophr Res. 2005;79:231-8.
  • 27. Kostakoğlu AE, Batur S, Tiryaki A, Göğüş A. Pozitif ve negatif sendrom ölçeğinin (PANSS) Türkçe uyarlamasının geçerlilik ve güvenilirliği. Turk Psikoloji Dergisi. 1999;14:23-32.
  • 28. Taylor S, Zvolensky MJ, Cox BJ, Deacon B, Heimberg RG, Ledley DR et al. Robust dimensions of anxiety sensitivity: development and initial validation of the Anxiety Sensitivity Index-3. Psychol Assess. 2007;19:176-88.
  • 29. Baek I, Lee E, Kim J. Differences in anxiety sensitivity factors between anxiety and depressive disorders. Depress Anxiety. 2019; 36:968-74.
  • 30. Allan NP, Capron DW, Raines AM, Schmidt NB. Unique relations among anxiety sensitivity factors and anxiety, depression, and suicidal ideation. J Anxiety Disord. 2014;28:266-75.
  • 31. Wheaton MG, Deacon BJ, McGrath PB, Berman NC, Abramowitz JS. Dimensions of anxiety sensitivity in the anxiety disorders: Evaluation of the ASI-3. J Anxiety Disord. 2012;26:401-8.
  • 32. Pozza A, Dèttore D. Psychometric evidence of the Italian Anxiety Sensitivity Index-3 (ASI-3) in patients with anxiety disorders and psychosis. Res Psychol Behav Sci. 2015;3:7-17.
  • 33. Rodriguez BF, Bruce SE, Pagano ME, Spencer MA, Keller MB. Factor structure and stability of the Anxiety Sensitivity Index in a longitudinal study of anxiety disorder patients. Behav Res Ther. 2004;42:79-91.
  • 34. Cosoff SJ, Hafner RJ. The prevalence of comorbid anxiety in schizophrenia, schizoaffective disorder and bipolar disorder. Aust N Z J Psychiatry. 1998;32:67- 72.
  • 35. Krabbendam L, Arts B, van Os J, Aleman A. Cognitive functioning in patients with schizophrenia and bipolar disorder: a quantitative review. Schizophr Res. 2005;80:137-49.
  • 36. Schmidt NB, Woolaway-Bickel K, Bates M. Evaluating panic-specific factors in the relationship between suicide and panic disorder. Behav Res Ther. 2001;39:635-49.
  • 37. Katz CE, Yaseen ZS, Mojtabai R, Galynker II. Panic as an independent risk factor for suicide attempt in depressive illness: findings from the national epidemiological survey on alcohol and related conditions (NESARC). J Clin Psychiatry. 2011;72:1628-35.
  • 38. Capron DW, Fitch K, Medley A, Blagg C, Mallott M, Joiner T. Role of anxiety sensitivity subfactors in suicidal ideation and suicide attempt history. Depress Anxiety. 2012;29:195-201.
  • 39. Cox BJ, Enns MW, Freeman P, Walker JR. Anxiety sensitivity and major depression: Examination of affective state dependence. Behav Res Ther. 2001;39:1349-56.
  • 40. Otto MW, Pollack MH, Fava M, Uccello R, Rosenbaum JF. Elevated Anxiety Sensitivity Index scores in patients with major depression: Correlates and changes with antidepressant treatment. J Anxiety Disord. 1995;9:117-23.
  • 41. Tedlow JR, Fava M, Uebelacker LA, Alpert JE, Nierenberg AA, Rosenbaum JF. Are study dropouts different from completers? Biol Psychiatry. 1996;40:668-70.
Cukurova Medical Journal-Cover
  • ISSN: 2602-3032
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1976
  • Yayıncı: Çukurova Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Bağırsak stomalı hastaların stomaya uyumlarını etkileyen faktörler: ilişkisel çalışma

Yasemin AKIL, Seçil TAYLAN

İlk ve acil yardım öğrencilerinin neonatal resusitasyona yönelik bilişsel becerilerinin geliştirilmesinde simülasyonun etkisi

Pınar DOĞAN, Bahar Nur KANBUR, Selmin KÖSE, Sonay BALTACI GÖKTAŞ

Meme kanseri hastalarının tamamlayıcı tedavilerin kullanımına ilişkin inanç ve deneyimleri: Kalitatif bir çalışma

Ayla TUZCU, Merve İPEK

Koksartrozda uygulanan çimentosuz total kalça protezinin klinik sonuçları

Melih BAĞIR, Ahmet YILMAZ

Bir eğitim hastanesinde farmakovijilans merkezine yönlendirilen yatan hastalardaki advers ilaç reaksiyonlarının analizi

Zakir KHAN, Emine ÖZ EKEMEN, Olcay KIROĞLU, Yusuf KARATAŞ

Bipolar bozukluk ve şizofrenide anksiyete duyarlılığı

Zeynep NAMLI, Lut TAMAM, Mehmet Emin DEMİRKOL, Soner ÇAKMAK

Sağlıklı Türk popülasyonunda sella turcica tiplerinin belirlenmesi

Sema ÖZANDAÇ POLAT, Ayşe Gül KABAKCI, Fatma Yasemin ÖKSÜZLER, Mahmut OKSÜZLER, Ahmet Hilmi YÜCEL

Corona Virüsü Hastalığı 2019 Pandemi tehdidi altında vatandaşların güvenli bir şekilde geri gönderilmesinin sağlanması

Saurabh SHRİVASTAVA, Prateek SHRİVASTAVA

Perkütan kapatmaya şiddetli pulmoner hipertansiyonu olan patent duktus arteriozusda şans verilebilir

Ömer TEPE, Çağlar ÖZMEN, Ali DENİZ, Nazan ÖZBARLAS, Mehmet TOPÇUOĞLU

Cleveland Adölesan Uykululuk Anketi’nin Türkçe’ye uyarlanması: Lise öğrencileri için geçerlik-güvenirlik çalışması

Songül ÇAĞLAR, Makbule TOKUR KESGİN