Açık cerrahi ile tedavi edilen inkarsere inguinal hernide hastane yatışı ile trombosit dağılım genişliği ilişkisi

Amaç: Çalışma, greftle tedavi edilen, inkarsere inguinal hernideki trombosit dağılım genişliğinin (PDW) cerrahi ile ilişkili bozukluklardaki inflamatuvar rolünü aydınlatmak için değerini araştırmayı amaçladı.Gereç ve Yöntem: İnguinal hernisi olan ve 75 sağlıklı olan 88 hastanın retrospektif tarama verilerini inceleyerek bir vaka kontrol çalışması yaptık. Hasta verileri demografik özellikleri, herni yerleşimi, hastanede kalış süresi ve hemogram parametrelerini içeriyordu. Trombosit ilişkili parametrelerde ölçüm EDTA'lı numune örneklerinden otomatize cihazlarla yapıldı.Bulgular: Ortalama defekt büyüklüğü 6 ila 75 mm arasında değişen inguinal herni için 25.3±17 mm idi. PDW değeri hasta grubunda sağlıklı gruba göre daha yüksekti. Ayrıca, trombositler hasta grubunda istatistiksel olarak daha yüksekti. Pearson korelasyon analizinde PDW hastanede kalış ile güçlü ve pozitif bir ilişki gösterdi.Sonuç: Trombosit dağılım genişliği ile hastanede kalış arasındaki güçlü pozitif korelasyonun, açık cerrahi ile tedavi ettiğimiz inguinal hernilerde hastane yatış süresi üzerinde yararlı bilgiler vereceğini düşünüyoruz.

Anahtar Kelimeler:

Kasık Fıtığı, Trombosit Dağılım Genişliği, Açık Cerrahi

Relationship between platelet distribution width and hospital stay in incarcerated inguinal hernia treated by open surgery

Purpose: The study aimed to investigate the value of platelet distribution width (PDW) in incarcerated inguinal hernia which was treated with graft to illuminate its inflammatory role in surgery-related disorders.Materials and Methods: We perormed a case-control study by retrospective screening data of the 88 patients with inguinal hernia and 75 healthy. Patients data included demographics, hernia location, hospital stay, and hemogram parameters. Platelet-related parameters were anayzled with automated devices from EDTA samples.Results: The mean defect size was 25.3±17 mm for inguinal hernia, which ranged 6 to 75 mm. The PDW value was higher in group A as compared with that of group B. Also, the platelets were statistically higher in group A than group B. In the Pearson correlation analysis, PDW showed a strong and positive relationship with a hospital stay. Conclusion: We suggest that a strong positive correlation of platelet distribution width with hospital stay can be useful in incarcerated inguinal hernia which we treated with grafted by open surgery.

Keywords:

Platelet Distribution Width, Incarcerated Inguinal Herni, Hospital Stay,

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1. Yang B, Jiang ZP, Li YR, Zong Z, Chen S. Long-term outcome for open preperitoneal mesh repair of recurrent inguinal hernia. Int J Surg. 2015;19:134-6.
2. Radu P, Bratucu M, Garofil D, Pasnicu C, Iorga C, Popa F et al. Molecular factors of failure in incisional hernia surgery. Chirurgia (Bucur). 2013;108:193-8.
3. de Hingh IH, Nienhuijs SW, Overdevest EP, Scheele K, Everts PA. Mesh fixation with autologous plateletrich fibrin sealant in inguinal hernia repair. Eur Surg Res. 2009;43:306-9.
4. Barbieri RL, Parreira SF, Studart SDV, AR DA-S, Duarte IDS, Leme PLS. Stem Cells hematopoietic niches and inflammatory response to different synthetic prosthesis implanted in rat with incisional hernias. Arq Bras Cir Dig. 2017;30:108-13.
5. Tadaki C, Lomelin D, Simorov A, Jones R, Humphreys M, daSilva M et al. Perioperative outcomes and costs of laparoscopic versus open inguinal hernia repair. Hernia. 2016;20:399-404.
6. Kilincalp S, Ekiz F, Basar O, Ayte MR, Coban S, Yilmaz B et al. Mean platelet volume could be possible biomarker in early diagnosis and monitoring of gastric cancer. Platelets. 2014;25:592-4.
7. Karaman H, Karakukcu C, Kocer D. Can mean platelet volume serve as a marker for prostatitis? Int J Med Sci. 2013;10:1387-91.
8. Topal F, Karaman K, Akbulut S, Dincer N, Dolek Y, Cosgun Y et al. The relationship between mean platelet volume levels and the inflammation in Helicobacter pylori gastritis. J Natl Med Assoc. 2010;102:726-30.
9. Ocakli B, Tuncay E, Gungor S, Sertbas M, Adiguzel N, Irmak I et al. Inflammatory markers in patients using domiciliary non-invasive mechanical ventilation: c reactive protein, procalcitonin, neutrophil lymphocyte ratio. Front Public Health. 2018;6:245.
10. Gu Nes ME, Deniz MM, Yilmaz S. Diagnostic value of platelet indices in acute appendicitis and comparison with histopathology. Ann Ital Chir. 2017;88:222-8.
11. Bozkurt S, Kose A, Erdogan S, Bozali GI, Ayrik C, Arpaci RB et al. MPV and other inflammatory markers in diagnosing acute appendicitis. J Pak Med Assoc. 2015;65:637-41.
12. Aktas G, Alcelik A, Tekce BK, Tekelioglu V, Sit M, Savli H. Red cell distribution width and mean platelet volume in patients with irritable bowel syndrome. Prz Gastroenterol. 2014;9:160-3.
13. Ulutas KT, Sarici IS, Arpaci A. Comparison of platelet distribution width and CA19-9 in resectable pancreas cancer. Med Arch. 2018;72:210-3.
14. Ulutas KT, Dokuyucu R, Sefil F, Yengil E, Sumbul AT, Rizaoglu H et al. Evaluation of mean platelet volume in patients with type 2 diabetes mellitus and blood glucose regulation: a marker for atherosclerosis? Int J Clin Exp Med. 2014;7:955-61.
15. Koksal H, Ates D, Nazik EE, Kucukosmanoglu I, Dogan SM, Dogru O. Predictive value of preoperative neutrophil-to-lymphocyte ratio while detecting bowel resection in hernia with intestinal incarceration. Ulus Travma Acil Cerrahi Derg. 2018;24:207-10.
16. Fan Z, Zhang Y, Pan J, Wang S. Acute appendicitis and mean platelet volume: a systemic review and meta-analysis. Ann Clin Lab Sci. 2017;47:768-72.
17. Willoughby AD, Lim RB, Lustik MB. Open versus laparoscopic unilateral inguinal hernia repairs: defining the ideal BMI to reduce complications. Surg Endosc. 2017;31:206-14.
18. Wakasugi M, Tei M, Akamatsu H. Single-incision totally extraperitoneal inguinal hernia repair after previous inguinal hernia repair. Surg Laparosc Endosc Percutan Tech. 2016;26:e149-e52.
19. Kahramanca S, Kaya O, Ozgehan G, Guzel H, Azili C, Gokce E et al. Are fibrinogen and complete blood count parameters predictive in incarcerated abdominal hernia repair? Int Surg. 2014;99:723-8.