Central venous catheter-related bloodstream infections: literature review

Santral venöz kateter (SVK) kullanımı düşük doğum ağırlıklı yenidoğanlar, kanserli çocuklar ve kistik fibro- zis ve hemofili hastaları gibi sık damar yolu ihtiyacı olan kronik hastalığı olan çoğu çocuk hasta grubunda oldukça faydalıdır. Santral venöz kateterler genellikle iyi tolere edilmekle beraber enfeksiyöz komplikasyon- lar olabilmekte ve artan morbidite, hospitalizasyon ve maliyete neden olabilmektedir. Çocuklarda vasküler erişim sıklıkla çok sınırlıdır. Bu durum periferal kan kültürü elde etmenin zorluğu ve santral yolun uzaklaş- tırılmasının işlevsel olmaması nedeniyle kateter-ilişkili kan dolaşım enfeksiyonlarının tanı ve tedavisini güç- leştirmektedir. Veriler kısıtlı olmakla beraber, santral venöz kateter-ilişkili enfeksiyonlarından (SVKE) korun- ma ve tedavisi ile ilgili yeni teknolojiler SVKE’lerin azalmasında etkili olabilmektedirler. Santral venöz kateter-ilişkili enfeksiyonların patogenezini ve altta yatan risk faktörlerini anlamak hayatı tehdit edici kompliksayonları azaltmak ve yeni tedavi stratejileri geliştirmek açısından çok önemlidir. (J Pediatr Inf 2013; 7: 25-30)

ntravasküler kateter ilişkili kan dolaşım enfeksiyonları: literatür özeti

The use of central venous catheters (CVC) is benefi- cial for the management of many groups of pediatric patients including low birth weight neonates, children with cancer, and those with chronic diseases that require frequent venous access such as cystic fibro- sis and hemophilia. These CVCs are usually well-tol- erated but infectious complications are relatively common and result in increased morbidity, hospital- ization, and cost. Vascular access is often limited in pediatric patients. This affects both the diagnosis and management of catheter-related bloodstream infec- tions (CR-BSIs) because obtaining a peripheral cul- ture may not be possible and line removal may not be feasible. Despite limited data for specific interven- tions, new technologies for the prevention and treat- ment of CR-BSIs are effective in reducing CR-BSIs. Understanding of the pathogenic process and under- lying risk factors of CR-BSIs is important in decreas- ing the life threatening complications and also improving the management strategies. (J Pediatr Inf 2013; 7: 25-30)

Kaynakça

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