Bebeklikte barsak florası gelişimi ve immun sisteme etkiler

Barsak florasının çok önemli bir kısmını oluşturduğu intestinal immun sistem yaşamın erken dönemlerinden itibaren infeksiyonlarla daha iyi mücadele ederken daha az allerji ve otoimmunite geliştirmek üzere programlanabilir. Gebelikteki diyetten başlayarak vajinal doğum şekli ve sinbiyotik özellikleri olan anne sütünün verilmesinin gastrointestinal flora gelişimine olumlu etkileri vardır. Bu floranın gelişimini destekleyecek pro-pre-sinbiyotiklerin kullanımı prematüre bebeklerde ağır infeksiyöz komplikasyonların ve özellikle nekrotizan enterokolitin azaltılmasında ve yüksek atopi riskli bebeklerde allerjinin gelişmesini engellemekte yararları olabilir

Development of intestinal flora in infancy and ıts effects on immune system

Intestinal immune system, in which intestinal flora play an important role, can be programmed to be more efficient against infections as well as producing less allergic and autoimmune disorders. Beginning with the diet in pregnancy, then by vaginal delivery and human milk -with its synbiotic effect - maturation of healthy gastrointestinal flora in infants can be supported. Probiotics, prebiotics,and synbiotics may be helpful in reducing severe infectious complications such as necrotising enterocolitis in preterm infants and preventing allergic disorders in infants with a high risk of atopy due to their positive effects on the development of intestinal microflora.

Kaynakça

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