ALİ ATAŞ, Alpay ÇAKMAK, Dost ZEYBEK, Salih DURAK

Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka

Bez dermatiti, sütçocuklarında en yaygın görülen hastalık- larından biri olup, en sık 9-12. aylarda rastlanır. Bez der- matitinin hafif formları kendiliğinden düzebilirken daha ciddi formları tıbbi tedaviye gereksinim duyar. Diğer topi- kal ajanlara yanıt alınamayan orta ve ciddi bez dermatit- lerinde kısa süreli, düşük potensli kortikosteroidler yararlı olabilir. Kullanılan kortikosteroid potent olduğunda veya uzun süreli kullanıldığında iatrojenik Cushing sendromuna neden olabilir. Bu çalışmada bez dermatiti tedavisi sırasın- da, topikal potent kortikosteroid olan klobetazol 17 propi- onat Dermovate % 0.05 krem kullanımı sonucu, iatroje- nik Cushing sendromu gelişen beş kız vaka sunulmuştur

Anahtar Kelimeler:

Cushing, iatrojenik, bez dermatiti

Five Cases of Iatrogenic Cushing’s Syndrome Due to the Use of A Topical Steroid in Diaper Dermatitis

Diaper dermatitis is one of the most common disorders in infants. The incidence of diaper dermatitis is highest in those between 9 and 12 months of age. While mild forms heal spontaneously, more severe forms may require medi- cal attention. A short duration of mild corticosteroid app- lication may be useful in moderate to severe cases of dia- per dermatitis which have not responded to other topical agents. Iatrogenic Cushing’s syndrome may be due to extended use of steroid or the potency of topical corticos- teroids. We report five cases of Cushing’s syndrome due to the use of a topical potent corticosteroid clobetazole 17 propionate 0.05 % cream in diaper dermatitis

Keywords:

Cushing, iatrogenic, diaper dermatitis,

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