Aort Kapak Kalsifikasyon Derecesi ile Epikardiyal Yağ Dokusu Kalınlığı İlişkisi

Artmış epikardiyal yağ dokusu kalınlığı, koroner arter hastalığının varlığı ve yaygınlığı, ateroskleroz,hipertansiyon, insülin direnci ,diabetes mellitus ,metabolik sendrom gibi hastalıklar ve bunların enflamatuar süreçleri ile ilişkili bulunmuştur. Bu çalışmada epikardiyal yağ dokusu kalınlığı ile ateroskleroz ve birçok hastalıkla birlikte gözlenen aort kapak kalsifikasyonu arasındaki ilişkiyi değerlendirmeyi amaçladık. Materyal ve Metod: Çalışmaya kardiyoloji polikliniğine başvuran ekokardiyografide aort kapak kalsifikasyonu olan (59 kadın, 55 erkek ,ortalama yaş: 78.0 ± 7.3 yıl) toplam 114 hasta alındı. Epikardiyal yağ dokusu kalınlığı ölçümü iki boyutlu ekokardiyografik yöntemle diastol sonunda yağ dokusu dansitesiyle uyumlu bölgeden yapıldı.Aort kapak kalsifikasyon derecelendirmesi de ekokardiyografik olarak ,Rosenhek skorlamasına göre yapıldı.Buna göre aort kapak kalsifikasyonu grade 1(kalsifikasyon saptanmadı) , grade 2 (hafif kalsifikasyon,küçük izole noktalanmalar),grade 3 (orta düzeyde kalsifikasyon,çoklu geniş noktalanmalar) ve grade 4 (ağır kalsifikasyon,bütün küspisleri içeren yaygın kalsifikasyon) şeklinde değerlendirildi.Çalışmamıza alınan hastalar aort kapak kalsifikasyon derecelendirmesine göre Grade 2-3 (grup1) ve 4 (grup2) şeklinde yer alıyordu.Aort kapakta kalsifikasyon saptanmayan hasta olmadığı için çalışmamızda Grade 1 hasta yoktu. Bulgular: Aort kapak kalsifikasyon derecelendirmesine göre ayrılan Grade 2-3 teki hastalarla Grade 4 hastaları karsılastırıldığında koroner arter hastalığı, hipertansiyon, diabetes mellitus ve hiperlipidemi açısından fark saptanmadı. Epikardiyal yağ dokusu kalınlığı ise Grade 4 (grup 2) de yer alan hastalarda Grade 2,3 (grup 1) dekilere göre daha yüksek saptandı. Sonuç: Hastalarda epikardiyal yağ dokusu kalınlığı ölçümü, ekokardiyografik değerlendirme sırasında aort kapak kalsifikasyonu ve derecesi hakkında da bilgi verebilecek kullanışlı bir parametre olabileceğini düşündürmüştür.

Background: Increased epicardial fat thickness (EFT) is associated with extension and burden of the coronary artery disease, hypertension, insulin resistance and inflammatory processes such as diabetes mellitus and metabolic syndrome. In this study we aimed to evaluate the relationship between EFT and aortic valve calcification grade (ACG). Materials and Method: The present study evaluated 114 patients referring to the cardiology outpatient clinic (59 females, 55 males mean age: 78.0±7.3 years) . EFT was measured with echocardiographic methods at the end of the diastole. The degree of aortic valvular calcification (ACG) in patients was determined with Rosenhek score. Briefly the AV calcifications were graded qualitatively as grade 1 (no calcification), grade 2 (mildly calcified; small isolated spots), grade 3 (moderately calcified; multiple larger spots); or grade 4 (heavily calcified; extensive calcification of all cusps). In our study patients devided three groups according to the ACG. Results: There was no difference between the groups in terms of coronary artery disease,hypertension, diabetes mellitus and hyperlipidemia. In Grade-4 ACG (group 2) EFT mean was higher than Grade-2-3 ACG (group 1). Conclusion: EFT thicknes in the patients may provide useful information about aortic valve calcification during the echocardiographic evaluation of patients.

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Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi
  • ISSN: 2147-9607
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2014

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