Bahittin KAHVECİ, İnci DOĞAN, Fatih İSLAMOĞLU, Fatih YILMAZ

BazıYeniPotansiyelBiyolojik 4-(Arylidenamino)-2, 4-dihidro-3H1,2,4-Triazol-3-one BileşiklerininMikrodalgadestekliSentezivepKaDeğerlerininBelirlenmesi

Bu çalışmada,sekiz yeni bazı potansiyel biyolojik aktif 4-(arilidenamino)-2,4-dihidro-1H-1,2,4-triazol-3-on bileşikleri mikrodalga yöntemi kullanılarak sentezlendi. Bu bileşiklerin yapıları farklı spektroskopik yöntemle (IR, 1H NMR, 13C NMR and elemental analiz) kullanılarak karakterize edildi. Bu bileşiklerin asit ayrışma sabitleri teorik olarak 25oC’de yirmi beş farklı çözücü içerisinde SPARC bilgisayar programı vasıtasıyla belirlendi. Çözücülerin asit ayrışma sabitleri üzerindeki etkileri tartışıldı

Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values

In the present study, eight new 4-(arylideneamino)-2,4-dihydro-1H-1,2,4-triazol-3-ones that may show some potential biological properties were synthesized using microwave method. These compounds were characterized by different spectroscopic techniques (IR, 1H NMR, 13C NMR and elemental analysis). Acid dissociation constants (pKa) were determined theoretically with SPARC computer program in different twenty five solvents at 25oC. The effects of solvents composition on the acid dissociation constants are discussed.

Keywords:

Acid dissociation constant, 4-Amino-1, 2 4-triazol, Imines, Microwave synthesis, NMR,

Tam Metin

Kaynak Göster

Bibtex	@araştırma makalesi { cbayarfbe254859, journal = {Celal Bayar University Journal of Science}, issn = {1305-130X}, eissn = {1305-1385}, address = {}, publisher = {Celal Bayar Üniversitesi}, year = {2016}, volume = {12}, pages = {275 - 281}, doi = {10.18466/cbujos.69902}, title = {Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values}, key = {cite}, author = {Kahveci, Bahittin and Doğan, İnci and İslamoğlu, Fatih and Yılmaz, Fatih} }
APA	Kahveci, B , Doğan, İ , İslamoğlu, F , Yılmaz, F . (2016). Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values . Celal Bayar University Journal of Science , 12 (2) , 275-281 . DOI: 10.18466/cbujos.69902
MLA	Kahveci, B , Doğan, İ , İslamoğlu, F , Yılmaz, F . "Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values" . Celal Bayar University Journal of Science 12 (2016 ): 275-281 <https://dergipark.org.tr/tr/pub/cbayarfbe/issue/23915/254859>
Chicago	Kahveci, B , Doğan, İ , İslamoğlu, F , Yılmaz, F . "Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values". Celal Bayar University Journal of Science 12 (2016 ): 275-281
RIS	TY - JOUR T1 - Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values AU - Bahittin Kahveci , İnci Doğan , Fatih İslamoğlu , Fatih Yılmaz Y1 - 2016 PY - 2016 N1 - doi: 10.18466/cbujos.69902 DO - 10.18466/cbujos.69902 T2 - Celal Bayar University Journal of Science JF - Journal JO - JOR SP - 275 EP - 281 VL - 12 IS - 2 SN - 1305-130X-1305-1385 M3 - doi: 10.18466/cbujos.69902 UR - https://doi.org/10.18466/cbujos.69902 Y2 - 2021 ER -
EndNote	%0 Celal Bayar Üniversitesi Fen Bilimleri Dergisi Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values %A Bahittin Kahveci , İnci Doğan , Fatih İslamoğlu , Fatih Yılmaz %T Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values %D 2016 %J Celal Bayar University Journal of Science %P 1305-130X-1305-1385 %V 12 %N 2 %R doi: 10.18466/cbujos.69902 %U 10.18466/cbujos.69902
ISNAD	Kahveci, Bahittin , Doğan, İnci , İslamoğlu, Fatih , Yılmaz, Fatih . "Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values". Celal Bayar University Journal of Science 12 / 2 (Ağustos 2016): 275-281 . https://doi.org/10.18466/cbujos.69902
AMA	Kahveci B , Doğan İ , İslamoğlu F , Yılmaz F . Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values. Celal Bayar Univ J Sci. 2016; 12(2): 275-281.
Vancouver	Kahveci B , Doğan İ , İslamoğlu F , Yılmaz F . Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values. Celal Bayar University Journal of Science. 2016; 12(2): 275-281.
IEEE	B. Kahveci , İ. Doğan , F. İslamoğlu ve F. Yılmaz , "Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values", Celal Bayar University Journal of Science, c. 12, sayı. 2, ss. 275-281, Ağu. 2016, doi:10.18466/cbujos.69902