Porfirinler biyolojik sistemlerdeki en önemli prostetik gruplar olarak bilinmektedirler. Bu çal mada, 2,3,7,8,12,13,17,18-oktaetilporfirinin sentezi gerçekle tirilmi tir. Bu amaç için ilk önce bir -halojenasyon reaksiyonu ile bütanalden 2-bromobütanal elde edilmi ve yine bütanal, morfolin ile etkile tirilerek 1morfolino-1-büten enamini sentezlenmi tir. 2-bromobutanal ve 1-morfolino-1-büten uygun etkile tirilerek 2,3-dietilsüksinaldehit elde edilmi tir. 2,3-Dietilsüksinaldehitin amonyum karbonat ile reaksiyonu sonucu 3,4-dietilpirol sentezlenmi tir. Total sentezin son basama nda ise 2,3,7,8,12,13,17,18oktaetilporfirin, 3,4-dietilpirol ile sulu formaldehidin asit katalizli kondensasyon reaksiyonu sonucu elde edilmi tir

The porphyrins are known as one of the most important prosthetic groups in biological systems. In this study, it is aimed to synthesize 2,3,7,8,12,13,17,18-octaethylporphyrin. For this purpose at first 2- bromobutanal was achieved from butanal via -halogenation reaction and also 1-morpholino-1-butene enamine was synthesized from butanal with an interaction of morpholine. 2-bromobutanal and 1-morpholino- 1-butene was reacted in suitable media and obtained 2,3-diethylsuccinaldehyde. 3,4-Diethylpyrrole was synthesized by treating 2,3-diethylsuccinaldehyde with ammonium carbonate. 2,3,7,8,12,13,17,18- Octaethylporphyrin was obtained from an interaction between 3,4-diethylpyrrole and aqueous formaldehydeunder acid catalyzed condensation reaction in the last step of total synthesis.