Meme Kanseri ve Fitokimyasallar

Fitokimyasallar bitkilerde ikincil metabolit olarak sentezlenen doğal, tedavi edici bileşiklerdir. Bu doğal bileşikler kanser sürecinde onkogenik veya tümör baskılayıcı etkileri ile patolojik durumlarda önemli düzenleyici etkilere sahiplerdir. Diyetin meme kanseri riski ile ilişkili değiştirilebilir bir etmen olduğunu gösteren çok sayıda çalışma mevcuttur ve anti-karsinojenik etkileri ile fitokimyasallar da bu etkiyi oluşturan etmenler arasında yer almaktadır. Fitokimyasal indeks ise fitokimyasal alımının değerlendirilmesinde kullanılan basit bir yöntem olup, diyet kalitesinin kronik hastalıklarla olan ilişkisinin belirlenmesinde önemli bir zemin oluşturabilir. Bu derleme yazıda diyetsel fitokimyasallar ve fitokimyasal indeksin, meme kanseri riski ile arasındaki ilişki tartışılmıştır

Breast Cancer and Phytochemicals

Phytochemicals are natural, therapeutic compounds that are synthesized as secondary metabolites in plants. These natural compounds have important regulatory effects in pathological conditions with oncogenic or tumor suppressive effects in the cancer process. There are a number of studies showing that diet is a changeable factor associated with breast cancer risk and phytochemicals with anticarcinogenic effects are among these factors. Phytochemical index is a simple method used in the evaluation of phytochemical uptake and may be an important basis for determining the relationship between diet quality and chronic diseases. In our review, main debate is about the association between dietary phytochemicals or phytochemical index and the risk of breast cancer

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