EZGİ TOPTAŞ BIYIKLI, ALİ EMRAH BIYIKLI, GAMZE AKBULUT

Glisemik İndeks, Glisemik Yük ve Kanser

Son yıllarda artış gösteren birçok kronik hastalığın temelinde yetersiz ve dengesiz beslenme yer almaktadır. Modern diyete geçiş getirdiği kolaylıkların yanında hazır ve işlenmiş besin tüketiminin artmasına yol açmıştır. İşlenmiş karbonhidrat kaynakları glisemik indeks (Gİ) ve glisemik yük (GY) bakımından zengindir. Yüksek Gİ ve GY'li diyetlerin diyabet gibi bazı kronik hastalıkların insidansını artırması kanserle ilişkisinin incelenmesine yönelik çalışmaları da artırmıştır. Yüksek Gİ ve GY'li diyetler insülin salınımını tetikleyerek insülin benzeri büyüme faktörü-1 (IGF-1) düzeyinde artışa neden olmakta, bu da bazı kanser türleri için risk sayılmaktadır. Gİ ve GY ile kanser riskini inceleyen çok sayıda çalışma olmasına rağmen sonuçlar net değildir. Kanser hastalarının diyetlerindeki Gİ ve GY değerinin prognoz üzerine etkilerini inceleyen çalışmalar ise oldukça sınırlıdır. Yüksek Gİ ve GY'li diyetlerin vücut ağırlık artışını tetikleyerek, obezite, diyabet, kanser gibi hastalıkların oluşum riskini artırabileceği unutulmamalı, Gİ ve GY değeri yüksek besinlerin tüketimi azaltılmalıdır

Glycemic Index, Glycemic Load and Cancer

It is found that there is inadequate and unbalanced diet in the basis of most chronical diseases that have increased in recent years. Modern diet beside its facilities causes to increase consumption of prepared and processed foods. Processed carbohydrate sources are rich of GI (Glycemic index) and GL (Glycemic load). Given the fact that high GI and GL diets increase the incidence of chronical diseases such as diabetes, hence the number of studies investigating their relationship with cancer has also increased consequently. As the diets of high GI and GL triggers insulin secretion it increases the level of IGF-1 and it is considered to be a risk for some types of cancer. Although there are lots of studies searching for the results are not clear. The studies that investigate the effect of GI and GL values of cancer patients’ diets on prognosis are quite limited. It should not be forgotten that high GI and GL diets trigger the risk of obesity, diabetes and cancer by increasing weight gain, so the consumption of the foods with high GI and GL should be reduced

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