Kolesistektomi Spesmenlerimizin Histopatolojik Sonuçları ve Malignite Sıklığı

Amaç: Kolesistektomi uygulanan olgularda safra kesesi hastalıklarının dağılımını belirlemek.Yöntemler: Hastanemizde Temmuz 2015-Temmuz 2016 tarihleri arasında herhangi bir nedenle kolesistektomi uygulanan toplam 116 olguya ait kolesistektomi materyalinin histopatolojik özellikleri gözden geçirildi. Olguların raporları yeniden değerlendirildi.Bulgular: Çalışmaya 87’si (%75) kadın, 29’u (%25) erkek olmak üzere toplam 116 olgu alındı. Olguların yaş aralığı 20-82, yaş ortalaması 50,98±15,28 idi. En çok rastlanan hastalıklar 108 olguda görülen kronik kolesistit ve 62 olguda görülen kolelitiazisdi. Ksantogranulomatöz kolesistitli iki olgumuzda safra kesesi intraoperatif olarak malignite açısından kuşkulu bulunmuştur. On yedi olguda metaplazi, üç olguda displazi ve iki olguda insidental olarak adenokarsinom tespit edildi. Sonuç: Kolesistektomi uygulanan olgularda safra kesesinde malign tümör insidansı düşüktür (%1,72). Klinik olarak bulgu göstermeyen malignitelerin saptanabilmesi veya ksantogranulomatöz kolesistit gibi malignite kuşkusu oluşturan bulguların ekarte edilmesi için kolesistektomi spesimenlerinin rutin olarak, yeterli sayıda örnekleme yapılarak histopatolojik incelemeye alınması gerektiğini düşünüyoruz.

Anahtar Kelimeler:

Safra kesesi, Histopatoloji, Malignite

Histopathologic Results of Our Colesystectomy Specimens and Malignancy Frequency

Aim: To determine the distribution of gall bladder diseases in cholecystectomy cases. Methods: Histopathologic features of cholecystectomy specimens from 116 cases, who underwent cholecystectomy between the dates July 2015 and July 2016, were reviewed. The reports of the cases were re-evaluated. Findings: A total of 116 cases, 87 (75%) female and 29 (25%) male, were included in the study. Their age ranged from 20 to 82, and the mean age was found as 50,98 ± 15,28. The most commonly seen diseases were chronic cholecystitis, present in 108 of the cases, and cholelithiasis, seen in 62 of them. In our two xanthogranulomatous cholecystitis cases gall bladder was suspected intraoperatively for malignancy. Metaplasia, dysplasia and incidental adenocarcinoma was detected in 17, 3 and 2 of the cases respectively. Results: The incidence of malignant gallbladder tumors is low in patients undergoing cholecystectomy (%1,72). In order to detect clinically asymptomatic malignancies or to exclude the cases which create malignancy suspect such as xanthogranulomatous cholecystitis, we think sufficient numbers of sampling and histopathological examinations are needed.

Keywords:

Gall bladder, Histopathology, Malignancy,

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