Cervical blood flow velocity values in patients with unilateral intracranial aneurysm: Preliminary results

Aim: Brain aneurysm is a balloon shaped dilatation of brain vessels as a result of attenuation of the vessel walls. The aim of this study was to evaluate the relationship between blood flow velocities in the right and left arterial vessels in an unruptured aneurysm and healthy group, and to investigate whether this analysis can help early diagnosis of aneurysm. Methods: Four aneurysm patients (four female, mean age 57.25 ± 0.75 years) and four healthy subjects (two female, 2 male male, mean age 36.35 ± 6.19 years) were included in the study. Blood flow velocity values of right and left internal carotid arteries, vertebral artery and right and left internal jugular veins were obtained during a cardiac cycle with phase contrast technique. Spearman's correlation analysis was applied to flow velocity values. Statistically significant blood flow similarities between right and left brain were investigated. Results: In the aneurysm group, there was a significant difference between right and left cervical arterial blood flow velocity values (p=0.001). Spearman correlation coefficient values between right and left arterial blood flow velocity values and right and left side arteriovenous blood flow velocity values were lower in the aneurysm group compared to the control group however, there was no statistical significance (p≥0.05 for all). Conclusion: The difference between the right and left arterial blood flow velocities obtained in the aneurysm group and the low correlation values may be useful in early diagnosis of aneurysm.

Tek taraflı intrakranial anevrizmalı hastalarda servikal kan akış hızı değerleri: Ön sonuçlar

Amaç: Beyin anevrizması damar çeperlerindeki zayıflama sonucu beyin damarlarında oluşan balon şeklinde genişlemedir. Bu araştırmanın amacı, kanamasız anevrizmalı ve sağlıklı grupta sağ ve sol arteriyel damarlardaki kan akış hızlarını değerlendirmek ve bu analizin anevrizma ön tanısına yardımcı olup olamayacağını araştırmaktır. Yöntemler: Araştırmaya dört anevrizma hastası (dört kadın, ortalama yaş 57,25 ± 0,75) ve dört sağlıklı denek (iki kadın, iki erkek, ortalama yaş 36,35 ± 6,19) dahil edildi. Sağ ve sol iç karotis arter, vertebral arter ve sağ ve sol iç jugular ven kan akış hızı değerleri faz kontrast tekniği ile bir kardiyak döngü boyunca elde edildi. Spearman’ın ilişki analizi akış hızı değerlerine uygulandı. Beyinin sağı ve solu arasındaki istatistiksel olarak anlamlı kan akış benzerlikleri araştırıldı. Bulgular: Anevrizma grubunda, sağ ve sol taraf servikal arteriyel kan akış hızı değerleri arasında anlamlı fark bulundu (p=0,001). Sağ ve sol arteriyel kan akış hızı değerleri arasındaki ve sağ ve sol taraf arteriyovenöz kan akış hızı değerleri arasındaki Spearman ilişki katsayı değerleri anevrizma grubunda kontrol grubuna göre düşüktü, ancak istatistiksel anlamlılık yoktu (hepsi için p≥0,05). Sonuç: Bu ön araştırmanın sonuçları, anevrizma grubunda elde edilen sağ ve sol arteriyel kan akış hızları arasındaki belirgin farkın ve düşük ilişki değerlerinin anevrizma tanısında faydalı olabileceğini düşündürdü.

Kaynakça

1. Doddasomayajula R, Chung B, Hamzei-Sichani F, Putman CM, Cebral JR. Differences in Hemodynamics and Rupture Rate of Aneurysms at the Bifurcation of the Basilar and Internal Carotid Arteries. AJNR Am J Neuroradiol. 2017;38:570-6.

2. Zhao L, Zhang L, Zhang X, Li Z, Tian L, Wang Y-XJ. An Analysis of 1256 Cases of Sporadic Ruptured Cerebral Aneurysm in a Single Chinese Institution. PLoS One. 2014;19:e85668.

3. Wang R, Zhang D, Zhao J, Wang S, Zhao Y, Niu H. A comparative study of 43 patients with mirror-like intracranial aneurysms: risk factors, treatment, and prognosis. Neuropsychiatr Dis Treat. 2014;10:2231-7.

4. Hu P, Qian Y, Lee CJ, Zhang HQ, Ling F. The energy loss may predict rupture risks of anterior communicating aneurysms: a preliminary result. Int J Clin Exp Med. 2015;8:4128-33.

5. Berg P, Beuing O. Multiple intracranial aneurysms: a direct hemodynamic comparison between ruptured and unruptured vessel malformations. Int J Comput Assist Radiol Surg. 2018;13:83-93.

6. Liu J, Fan J, Xiang J, Zhang Y, Yang X. Hemodynamic characteristics of large unruptured internal carotid artery aneurysms prior to rupture: a case control study. J Neurointerv Surg. 2016;8:367-72.

7. Gwilliam MN, Hoggard N, Capener D, Singh P, Marzo A, Verma PK et al. MR derived volumetric flow rate waveforms at locations within the common carotid, internal carotid, and basilar arteries. J Cereb Blood Flow Metab. 2009;29:1975-82.

8. El Sankari S G-JC, Fichten A, Godefroy O, Serot JM, Deramond H, Meyer ME, et al. Cerebrospinal fluid and blood flow in mild cognitive impairment and Alzheimer's disease: a differential diagnosis from idiopathic normal pressure hydrocephalus. Fluids Barriers CNS. 2011;8:12.

9. Boussel L, Rayz V, Martin A, Acevedo-Bolton G, Lawton MT, Higashida R et al. Phase-Contrast Magnetic Resonance Imaging Measurements in Intracranial Aneurysms In Vivo of Flow Patterns, Velocity Fields, and Wall Shear Stress: Comparison with Computational Fluid Dynamics. Magn Reson Med. 2009;61:409-17.

10. Karmonik C, Yen C, Grossman RG, Klucznik R, Benndorf G. Intra-aneurysmal flow patterns and wall shear stresses calculated with computational flow dynamics in an anterior communicating artery aneurysm depend on knowledge of patient-specific inflow rates. Acta Neurochir (Wien). 2009;151:479-85.

11. Hussein AE, Brunozzi D, Shakur SF, Ismail R, Charbel FT, Alaraj A. Cerebral Aneurysm Size and Distal Intracranial Hemodynamics: An Assessment of Flow and Pulsatility Index Using Quantitative Magnetic Resonance Angiography. Neurosurgery. 2018;83:660-5.

12. Alperin N, Vikingstad EM, GomezAnson B, Levin DN. Hemodynamically independent analysis of cerebrospinal fluid and brain motion observed with dynamic phase contrast MRI. Magn Reson Med. 1996;35:741-54.

13. Filatova OV, Sidorenko AA, Skorobogatov YY. Age and Sex Dependence of Hemodynamic Parameters of Human Internal Carotid Arteries. Hum Physiol. 2014;40:554-62.

14. Salk İ, Yıldız G, Eğilmez H, Atalar MH, Candan F, Çetin A. Carotid artery Doppler ultrasonography in patients with chronic kidney disease. Med Sci Monit. 2014;20:11-7.

15. Al-Eqabi DAM, Al-Sıaıdy WF, Al-Sabbagh AAJ, Al-Kırwi IN. Internal Carotid Peak-Systolic and End-Diastolic Velocities are the Sensitive Parameters in Predicting Conditions in Type 2 Diabetes. J Biomed Bioeng. 2013;4:90-2.

16. Hope TA, Hope MD, Purell DD, von Morze C, Vigneron DB, Alley MT et al. Evaluation of intracranial stenoses and aneurysms with accelerated 4D flow. Magn Reson Imaging. 2010;28:41-6.

Kaynak Göster

63 48

Arşiv
Sayıdaki Diğer Makaleler

Retrospective analysis of risk factors for development of biliary fistula after liver cyst hydatid surgery

Emin KÖSE, Nilay Tuğba BAZ, Deniz TAZEOĞLU, Mehmet Emin GÜRBÜZ, Hasan TOK, Ayhan ÖZSOY, Servet Rüştü KARAHAN

Assessment of relationship between serum magnesium and serum glucose levels and HOMA-IR in diabetic and prediabetic patients

Gülçin ŞAHİNGÖZ ERDAL, Faruk KARANDERE, Fuat MISIROĞLU, Işıl ÖZBAŞ TEVETOĞLU, YILDIZ OKUTURLAR, Hakan KOÇOĞLU, Mehmet HURŞİTOĞLU

Intragastric balloon therapy for obesity: Is it safe and effective?

ONUR BAYRAKTAR, Abdullah Alp ÖZÇELİK, Ahmet Ragıp ÖKTEMGİL, Barış BAYRAKTAR

Cervical blood flow velocity values in patients with unilateral intracranial aneurysm: Preliminary results

ENGİN TEKİN, MURAT PEHLİVAN, ÖMER KİTİŞ

Dorsal approach for excision of Morton’s interdigital neuroma: A mid-term follow-up study

Haluk ÇELİK, Metin UZUN

Comparing Efficacy of Surgicel ® Application with Nasal Packing in Epistaxis

Tevfik SÖZEN, Övsen ÖNAY, Seyit Mehmet CEYLAN

Can the quick Sequential Organ Failure Assessment (qSOFA) score, combined with plasma lactate concentration, predict the mortality for patients with infections in the emergency department?

Mustafa KORKUT, Cihan BEDEL

Thymosin beta-4 A/T polymorphism and acute coronary syndrome risk

Melike GEZEN, Ümit YILMAZ, Osman FAZLIOĞULLARI, Nesibe YİLMAZ, cem HOROZOĞLU, Arzu ERGEN, ŞAKİR ÜMİT ZEYBEK

The right coronary artery originating from the left anterior descending artery: A variant of single coronary artery anomaly

YAKUP ALSANCAK, Sina ALİ

Evaluation of inflammatory markers in patients with migraine

Aysel TEKESİN, ABDÜLKADİR TUNÇ