Bünyamin MUSLU, Selda MUSLU, Aslı DEMİR, Pınar DURAK, Özcan ERDEMLİ

Prekürarizasyon süksinilkoline bağlı gelişen postoperatif miyaljiyi önler mi?

Amaç: Prekürarizasyon işleminin süksinilkoline bağlı postoperatif miyaljiyi (POM) önlemedeki etkinliğini ve fasikülasyonlar ile POM arasındaki korelasyonu araştırdık. Yöntem: Çalışmaya, genel anestezi altında elektif minör cerrahi uygulanacak fiziksel durumu ASA I olan 48 hastalar dahil edildi. Randomize edilen hastalara 1.5 mg kg1 süksinilkolin uygulamasından 3 dakika önce 0.01 mg kg1 veküronyum, 0.02 mg kg'1 sisatraküryum ya da serum fizyolojik kullanıldı. Bütün hastalara tiyopental, fentanil ve izofluran ile standardize edilmiş genel anestezi tekniği uygulandı. Fasikülasy onların ve POM şiddetinin değerlendirilmesi dört puanlı skalalar ile yapıldı. Bulgular: Fasikülasy onlar, veküronyum ve sisatraküryum gruplarında serum fizyolojik grubuna göre daha az gözlendi (p

Anahtar Kelimeler:

Ameliyat sonrası dönem, Ağrı, Süksinilkolin, Nöromüsküler depolarizasyon ajanları, Ameliyat sonrası komplikasyonlar

Does precurarization prevent succinylcholine induced postoperative myalgia?

Objective: We investigated the efficacy of precurarization in preventing succinylcholine-induced postoperative myalgia (POM) and the correlation between fasciculations and POM. Method: This study included 48 patients (ASA I) scheduled for elective minor surgery. The patients were randomized to receive vecuronium 0.01 mg kg1, cisatracurium 0.02 mg kg'1 or saline, 3 minutes prior to 1.5 mg kg'1 of succinylcholine. Standard general anesthetic technique by thiopental, fentanyl and isoflurane was used for all the patients. The intensities of fasciculations and POM were assessed using four point scales. Results: Fasciculations were observed less frequently in the vecuronium and cisatracurium groups compared with the saline group (p< 0.05). There were no differences among the groups with respect to the incidence and severity of POM. There was no correlation between the incidences and intensities of fasciculations and POM. Conclusion: Precurarization did not effect the incidence and severity of succinylcholine-induced POM and there is no correlation between succinylcholine-induced fasciculations and POM.

Keywords:

Postoperative Period, Pain, Succinylcholine, Neuromuscular Depolarizing Agents, Postoperative Complications,

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