Pediatrik bir olguda yarık damak operasyonu sırasındaki malign hipertermi şüphesi
Malign hipertermi (MH) genel anestezi esnasında volatil ajanların veya depolarizan kas gevşeticilerin kullanımı ile tetiklenen, iskelet kaslarının hipermetabolik myopatisi olup nadir fakat hayatı tehdit edici bir durumdur. Daha önceki genel anestezi deneyimi sırasında malign hipertermiye ait bir hikayesi olmayan 14 aylık bir çocukta, yarık damak nedeniyle sevoşuran kullanılarak gerçekleştirilen genel anestezi esnasındaki MH şüphesi uyandıran klinik parametreleri sunmayı amaçladık. Malign hipertermide başarılı tedavi; erken hızlı tanı, tetikleyici ajan maruziyetinin hızla sonlandırılması, yeterli dozlarda dantrolenin iv dozunun verilmesi ve semptomatik tedavinin başlatılmasına dayalıdır.
Suspected malignant hyperthermia in a pediatric patient during the cleft palate surgery
Malignant hyperthermia (MH) is a rare, but life-threatining condition which is the hypermetabolic myopathy of skeleatal muscles triggered by the use of volatile agents or depolarizing muscle relaxants during general anesthesia. We aimed at presenting the clinical parameters which evoke suspicion of MH during general anesthesia by using sevofluran in a 14-month-old patient who had a cleft palate surgery, and who did not have any history of MH experience before. Success of the treatment of malignant hyperthermia is based on early and fast diagnosis, immediate cessation of triggering agents, intravenous administration of dantrolene in a sufficient dosage and beginning an adequate symptomatic treatment.
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