Amaç: Çalışmada, kardiyak arrest olgularında spontan dolaşımın geri dönüşü beklentisinin öngö- rülebilmesine yönelik olarak nötrofil-lenfosit ve platelet-lenfosit oranlarıyla spontan dolaşımın geri dönüşü arasındaki ilişkinin araştırılması amaçlandı. Yöntem: Acil servise 01 Ekim 2016-01 Haziran 2018 tarihlerinde başvuran hastalardan kardiyak arrest tanısı alanlar belirlendi. Demografik veriler, tam kan parametreleri, nötrofil-lenfosit ve platelet-lenfosit oranları, spontan dolaşımın geri dönüp dönmediği ile kardiyopulmoner resüsitas- yon süreleri kaydedildi. Hastalar, spontan dolaşımın geri döndüğü ve dönmediği olmak üzere 2 gruba ayrıldı. İki grup için nötrofil-lenfosit ve platelet-lenfosit oranları istatistiksel olarak analiz edildi. Bulgular: Çalışmaya toplam 216 olgu dahil edildi. Olguların 54’ünde (%25) spontan dolaşımın geri döndüğü bulundu. Tam kan parametreleri değerlendirildiğinde, beyaz küre, platelet ve nötrofil sayıları, nötrofil-lenfosit ve platelet-lenfosit oranları için spontan dolaşımı geri dönen ve dönme- yen gruplar arasında istatistiksel olarak anlamlı fark bulundu (p
Objective: The present study aimed to investigate the relationship between return of spontane- ous circulation (ROSC) and the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) regarding the prediction of ROSC in cardiac arrest (CA) cases. Method: Among the patients who presented to the emergency department between October 1, 2016 and June 1, 2018, cases that received the diagnosis of cardiac arrest were identified. Demographic data, complete blood count (CBC) parameters, NLR and PLR, whether ROSC was achieved or not, and time to cardiopulmonary resuscitation were recorded. The patients were divided into two groups as patients in whom ROSC was achieved and those in whom ROSC was not achieved. NLR and PLR were compared between the groups and statistically analyzed. Results: In total, 216 patients were included in the study. ROSC was achieved in 54 (25%) cases. When CBC parameters were evaluated, statistically significant differences were found between the white blood cell, platelet, and neutrophil counts as well as NLR and PLR values of the groups (p
Durila M. Reversible causes of cardiac arrest 4 “Ts” and 4 “Hs” can be easily diagnosed and remembered follo- wing general ABC rule, Motol University Hospital app- roach. Resuscitation. 2018;126:e7. https://doi.org/10.1016/j.resuscitation.2018.03.013 https://www.resuscitationjournal.com/article/S0300- 9572(18)30123-0/pdf. [Accessed 08 May 2019].
Mangla A, Daya MR, Gupta S. Post-resuscitation care for survivors of cardiac arrest. Indian Heart J. 2014;66 Suppl 1:S105-12. https://doi.org/10.1016/j.ihj.2013.12.028
Truhlar A, Deakin CD, Soar J, et al. European Resuscitation Council Guidelines for Resuscitation 2015: Section 4. Cardiac arrest in special circumstan- ces. Resuscitation. 2015;95:148-201. https://doi.org/10.1016/j.resuscitation.2015.07.017
Weiser C, Schwameis M, Sterz F, et al. Mortality in patients resuscitated from out-of-hospital cardiac arrest based on automated blood cell count and neut- rophil lymphocyte ratio at admission. Resuscitation. 2017;116:49-55. https://doi.org/10.1016/j.resuscitation.2017.05.006
Skrifvars MB, Vayrynen T, Kuisma M, et al. Comparison of Helsinki and European Resuscitation Council “do not attempt to resuscitate” guidelines, and a termination of resuscitation clinical prediction rule for out-of-hospital cardiac arrest patients found in asystole or pulseless electrical activity. Resuscitation. 2010;81:679-84. https://doi.org/ 10.1016/j.resuscitation.2010.01.033
Qin B, Ma N, Tang Q, et al. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were useful markers in assessment of inflammatory respon- se and disease activity in SLE patients. Modern Rheumatology. 2016;26:372-6. https://doi.org/10.3109/14397595.2015.1091136
Temiz A, Gazi E, Gungor O, et al. Platelet/lymphocyte ratio and risk of in-hospital mortality in patients with ST-elevated myocardial infarction. Med Sci Monit. 2014;20:660-5. https://doi.org/10.12659/MSM.890152
Eftestol T, Wik L, Sunde K, Steen PA. Effects of cardio- pulmonary resuscitation on predictors of ventricular fibrillation defibrillation success during out-of-hospital cardiac arrest. Circulation. 2004;110:10-5. https://doi.org/10.1161/01.CIR.0000133323.15565.75
Horne BD, Anderson JL, John JM, et al. Which white blood cell subtypes predict increased cardiovascular risk? J Am Coll Cardiol. 2005;45:1638-43. https://doi.org/10.1016/j.jacc.2005.02.054
Tokgoz S, Keskin S, Kayrak M, Seyithanoglu A, Ogmegul A. Is neutrophil/lymphocyte ratio predict to short-term mor- tality in acute cerebral infarct independently from infarct volume? J Stroke Cerebrovasc Dis. 2014;23:2163-8. https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.04.007
Costa G, Ruscelli P, Balducci G, et al. Clinical strategies for the management of intestinal obstruction and pseudo-obstruction. A Delphi Consensus study of SICUT (Societa Italiana di Chirurgia d’Urgenza e del Trauma). Annali italiani di chirurgia. 2016;87:105-17.
Forget P, Khalifa C, Defour JP, Latinne D, Van Pel MC, De Kock M. What is the normal value of the neutrophil-to- lymphocyte ratio? BMC research notes. 2017;10:12. https://doi.org/10.1186/s13104-016-2335-5
Msolli MA, Beltaief K, Bouida W, et al. Value of early change of serum C reactive protein combined to modi- fied Alvarado score in the diagnosis of acute appendi- citis. BMC Emergency Medicine. 2018;18:15. https://doi.org/10.1186/s12873-018-0166-5
Altintas O, Altintas MO, Tasal A, Kucukdagli OT, Asil T. The relationship of platelet-to-lymphocyte ratio with clinical outcome and final infarct core in acute ische- mic stroke patients who have undergone endovascular therapy. Neurol Res. 2016;38:759-65. https://doi.org/10.1080/01616412.2016.1215030
White NJ, Leong BS, Brueckner J, et al. Coagulopathy during cardiac arrest and resuscitation in a swine model of electrically induced ventricular fibrillation. Resuscitation. 2011;82:925-31. https://doi.org/10.1016/j.resuscitation.2011.02.034
Chen SY, Wang SH, Weng YM, et al. Successful resusci- tation of out of hospital cardiac arrest patients in the emergency department. Signa Vitae. 2011;6:20-6. https://doi.org/10.22514/SV61.052011.3
Qi Z, An L, Liu B, et al. Patients with out-of-hospital cardiac arrest show decreased human leucocyte antigen-DR expression on monocytes and B and T lymphocytes after return of spontaneous circulation. Scand J Immunol. 2018;88:e12707. https://doi.org/10.1111/sji.12707 https://www.ncbi.nlm.nih.gov/pubmed/30270439. [Accessed 08 May 2019].
Leliefeld PH, Koenderman L, Pillay J. How Neutrophils Shape Adaptive Immune Responses. Front Immunol. 2015;6:471. https://doi.org/10.3389/fimmu.2015.00471
Liaya M, Shimizu M, Takahashi K, et al. Combination of hemoglobin and low-flow duration can predict neuro- logical outcome in the initial phase of out-of-hospital cardiac arrest. J Crit Care. 2018;47:269-73. https://doi.org/10.1016/j.jcrc.2018.07.013
Albaeni A, Eid SM, Akinyele B, Kurup LN, Vaidya D, Chandra-Strobos N. The association between post resuscitation hemoglobin level and survival with good neurological outcome following Out Of Hospital cardi- ac arrest. Resuscitation. 2015;99:7-12. https://doi.org/10.1016/j.resuscitation.2015.11.015
Ameloot K, Genbrugge C, Meex I, et al. Low hemoglo- bin levels are associated with lower cerebral saturati- ons and poor outcome after cardiac arrest. Resuscitation. 2015;96:280-6. https://doi.org/10.1016/j.resuscitation.2015.08.015