Transrektal ultrasonografi eşliğinde alınan prostat iğne biyopsisinin erektil fonksiyon üzerine etkisi
AMAÇ: Transrektal ultrasonografi eşliğinde prostat biyopsisinin (TRUSBx) erektil fonksiyon üzerine etkisini incelemektir. GEREÇ ve YÖNTEM: Çalışmaya Mart 2013 – Aralık 2013 tarihleri arasında transrektal ultrasonografi eşliğinde prostat biyopsisi uygulanan 81 hasta dahil edildi. Hastalara işlemden önce ve 2., 4., 8. haftalarda Uluslar Arası Erektil İşlev - Erektil Fonksiyon (IIEF-EF) anket formu uygulandı. Kanser tanılı hastalar 4. hafta sonrasında çalışmadan çıkarıldı. Benign patolojili hastalar komplikasyon durumları bakımından alt gruplara ayrıldı. BULGULAR: Hastaların ortalama yaşı 62,9 (38–75) yıldı. IIEF-EF skoru 2. hafta kontrollerinde istatistiksel anlamlı olarak azaldı (p=0,004). Dördüncü hafta kontrollerinde benign patolojili hasta grubunda IIEFEF skoru başlangıç skoruyla karşılaştırıldığında istatistiksel anlamlı fark göstermezken (p=0,226), kanser tanılı hasta grubunda istatistiksel anlamlı olarak azaldı (p
The effect of ultrasound guided prostate needle biopsy on the erectile function
OBJECTIVE: To search the effect of transrectal ultrasonography-guided prostate biopsy (TRUS-Bx) on the erectile function. MATERIAL and METHODS: The study included 81 patients who underwent TRUS-Bx between March 2013 and December 2013. International Index of Erectile Function - Erectile Function Domain (IIEF-EF) questionnaire was completed before, and 2nd, 4th, 8th week after the intervention. The patients with cancer diagnosis were excluded after the fourth week. The cancer-free patients were divided into subgroups in terms of complication status. RESULTS: The mean age of the patients was 62.9 (38–75) years. IIEF-EF score decreased statistically significant in the 2nd week controls (p=0.004). In the 4th week control, there was no significant difference of the IIEF-EF score in the group of the cancer-free patients when compared with baseline score (p=0.226); however, it decreased statistically significant in the group of patients with cancer diagnosis (p
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- Hodge KK, McNeal JE, Terris MK, Stamey TA. Random systematic
versus ultrasound guided transrectal core biopsies of the prostate. J
Urol 1989;142:71–4.
- Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM.
Estimates of worldwide burden of cancer in 2008: GLOBOCAN
2008. Int J Cancer 2010;127:2893–917. [CrossRef]
- Loeb S, Vellekoop A, Ahmed HU, Catto J, Emberton M, Nam R,
et al. Systemic review of complications of prostate biopsy. Eur Urol
2013;64:876–92. [CrossRef]
- Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der
Kwast T, et al. EAU guidelines on prostate cancer. part 1: screening,
diagnosis, and local treatment with curative intent -update 2013.
Eur Urol 2014;65:124–37. [CrossRef]
- Ganeswaran D, Sweeney C, Yousif F, Lang S, Goodman C, Nabi
G. Population-based linkage of health records to detect urological
complications and hospitalisation following transrectal ultrasoundguided
biopsies in men suspected of prostate cancer. World J Urol
2012;32:309–15. [CrossRef]
- Li H, Yan W, Zhou Y, Ji Z, Chen J. Transperineal ultrasoundguided
saturation biopsies using 11-region template of prostate:
report of 303 cases. Urology 2007;70:1157–61. [CrossRef]
- Chiang IN, Chang SJ, Pu YS, Huang KH, Yu HJ, Huang CY.
Major complications and associated risk factors of transrectal
ultrasound guided prostate needle biopsy: a retrospective study
of 1875 cases in Taiwan. J Formos Med Assoc 2007;106:929–34.
[CrossRef]
- Chrisofos M, Papatsoris AG, Dellis A, Varkarakis IM, Skolarikos
A, Deliveliotis C. Can prostate biopsies affect erectile function?
Andrologia 2006;38:79–83. [CrossRef]
- Klein T, Palisaar RJ, Holz A, Brock M, Noldus J, Hinkel A. The
impact of prostate biopsy and periprostatic nerve block on erectile
and voiding function: a prospective study. J Urol 2010;184:1447–
52. [CrossRef]
- Akbal C, Türker P, Tavukçu HH, Simşek F, Türkeri L. Erectile
function in prostate cancer-free patients who underwent prostate
saturation biopsy. Eur Urol 2008;53:540–5. [CrossRef]
- Aktoz T, Kaplan M, Turan U, Memis D, Atakan IH, Inci O.
‘Multimodal’ approach to management of prostate biopsy pain
and effects on sexual function: efficacy of levobupivacaine adjuvant
to diclofenac sodium –a prospective randomized trial. Andrologia
2010;42:35–40. [CrossRef]
- Tuncel A, Kirilmaz U, Nalcacioglu V, Aslan Y, Polat F, Atan A. The
impact of transrectal prostate needle biopsy on sexuality in men
and their female partners. Urology 2008;71:1128–31. [CrossRef]
- Helfand BT, Glaser AP, Rimar K, Zargaroff S, Hedges J, McGuire
BB, et al. Prostate cancer diagnosis is associated with an increased
risk of erectile dysfunction after prostate biopsy. BJU Int
2013;111:38–43. [CrossRef]
- Fujita K, Landis P, McNeil BK, Pavlovich CP. Serial prostate biopsies
are associated with an increased risk of erectile dysfunction in men
with prostate cancer on active surveillance. J Urol 2009;182:2664–
9. [CrossRef]
- Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J,
Mishra A. The international index of erectile function (IIEF): a
multidimensional scale for assessment of erectile dysfunction.
Urology 1997;49:822–30.
- Cappelleri JC, Rosen RC, Smith MD, Mishra A, Osterloh IH.
Diagnostic evaluation of the erectile function domain of the
international Index of Erectile Function. Urology 1999;54:346–51.
- Heidenreich A, Bellmunt J, Bolla M, Joniau S, Mason M, Matveev
V, et al. EAU guidelines on prostate cancer. Part 1: screening,
diagnosis, and treatment of clinically localised disease. Eur Urol
2011;59:61–71. [CrossRef]
- Bjurlin MA, Carter HB, Schellhammer P, Cookson MS, Gomella
LG, Troyer D, et al. Optimization of initial prostate biopsy in
clinical practice: sampling, labeling and specimen processing. J
Urol 2013;189:2039–46. [CrossRef]
- Schoots IG, Roobol MJ, Niebboer D, Bangma CH, Steyerberg
EW, Hunink MG. Magnetic resonance imaging-targeted biopsy
may enhance the diagnostic accuracy of significant prostate
cancer detection compared to standard transrectal ultrasoundguided
biopsy: a systematic review and meta-analysis. Eur Urol
2015;68:438–50. [CrossRef]
- De Nunzio C, Lombardo R, Presicce F, Bellangino M, Finazzi Agro
E, Gambrosier MB, et al. Transrectal-ultrasound prostatic biopsy
preparation: rectal enema vs. mechanical bowel preparation. Cent
European J Urol 2015;68:223–8. [CrossRef]