İdiopatik erkek infertilitesinde antioksidan kompleks tedavinin etkinliğinin değerlendirilmesi

AMAÇ: İnfertil erkeklerin semen analizlerinde görülen oligoastenoteratozoospermi durumunun %30’undan fazlasında etiyolojik bir neden bulunamaz ve idiopatik infertilite olarak tanımlanır. Bu çalışmanın amacı, etiyolojik bir neden tespit edilemeyen ve idiopatik erkek infertilitesi olarak kabul edilen hastalarda antioksidan kompleks kullanımının, semen parametreleri üzerindeki etkisini değerlendirmektir. GEREÇ VE YÖNTEM: Çalışmaya, Ocak 2018 – Ocak 2020 arasında idiopatik erkek infertilitesi tanısı konulan, primer veya nüks varikoseli, hormonal patolojisi olmayan ve testis hacimleri normal olarak değerlendirilen 92 hasta alınmıştır. Tüm hastalar, içeriğinde L-arjinin, L-karnitin, Magnezyum, Ginseng ekstresi, çinko, Koenzim Q10, Vitamin D, Selenyum olan ve gıda takviye edici olarak adlandırılan preparatlardan, yaklaşık sekiz saatte bir olmak üzere günde üç kez düzenli olarak altı ay boyunca kullandı. Tedavi öncesinde ve sonrasındaki 6. ayda semen parametreleri çalışılarak, değişimler analiz edildi. BULGULAR: Hastaların yaş aralığı 20–40 (ortalama: 28,9) idi. Antioksidan tedavi öncesi ve sonrası semen parametreleri karşılaştırıldığında semen hacminde anlamlı bir değişim gözlenmedi. Sperm sayısı, progresif ve total motilite incelendiğinde altı aylık tedavi sonrası anlamlı düzelme mevcuttu (p

Evaluation of the effectiveness of antioxidant complex treatment in idiopatic male infertility

OBJECTIVE: In male infertility in more than 30% of oligoasthenoteratozoospermia patients etiological cause cannot be found and it is defined as idiopathic infertility. The aim of this study is to evaluate the effect of antioxidant complex treatment on semen parameters in patients whose etiological cause can not be identified and considered as idiopathic male infertility. MATERIAL AND METHODS: Ninety two patients patients with idiopathic male infertility diagnosed between January 2018 and January 2020, without primary or recurrent varicocele, without hormonal pathology and with normal testicular volumes were included in the study. All patients used three times a day regularly for 6 months, from supplements that contain L-arginine, L-carnitine, Magnesium, Ginseng extract, zinc, Coenzyme Q10, Vitamin D and Selenium. The semen parameters were evaluated before and 6 months after the treatment and the changes were analyzed. RESULTS: The age range of the patients was 20-40 (mean: 28.9). Semen parameters were compared before and after antioxidant treatment and there was no significant change in semen volume. There was a significant improvement after 6 months of treatment in sperm count, progressive and total motility (p

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