Olfaktor referans sendromu: Olgu sunumu

Olfaktor referans sendromu (ORS), kişinin bedeninden kötü koku yaydığı yanlış ve ısrarlı inancı ile giden bedensel tipte bir sanrısal bozukluktur. ORS hastaları kokudan kendilerini sorumlu hisseder ve büyük utanç yaşarlar. Hastalar sıklıkla toplum içine çıkmaz, sosyal ve mesleksel iletişimlerini kısıtlarlar. Bu yazıda, bedeninin kötü koku yaydığı sanrısı ve bunun neden olduğu depresyon belirtileri olan, essitalopram ve olanzapin kombinasyonu ile belirgin düzelme gösteren bir olgu sunulmuştur. (Anadolu Psikiyatri Derg 2016; 17(3):31-34).

Olfactory reference syndrome: a case report

Olfactory reference syndrome (ORS) is a delusional disorder of somatic type of characterized by persistent wrong belief that the person has bad odor originating from his/her body. Patients with ORS feel responsible for themselves for the bad odor and shame. Patients often withdraw from the society, they restrict their social and occupational communication. In this report we present a case with a delusion related to bad odor of his body and secondary depressive symptoms who presented significant improvement with the combination of escitalopram and olanzapine. (Anatolian Journal of Psychiatry 2016; 17(3):31-34).

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1. Phillips KA, Menard W. Olfactory reference syndrome: demographic and clinical features of imagined body odor. Gen Hosp Psychiatry 2011; 33:398-406.

2. Pryse-Philips W. An olfactory reference syndrome. Acta Psychiatr Scand 1971; 47:484-509.

3. Thomas CS. Dysmorphobia and monosymptomatic hypochondrisis (letter). Am J Psychiatry 1985; 142:1121.

4. Tilley H. Three cases of parosmia: causes and treatment. Lancet 1895; 146:907-908.

5. Videbech T. Chronic olfactory paranoid syndromes. A contribution to the psychopathology of the sense of smell. Acta Psychiatr Scand 1966; 42:182-213.

6. Bourgeois M, Paty J. Autodysosmophobia and the psychopathology of smell (a propos of 7 cases). Bord Med 1972; 17:2269-2286.

7. Bishop ER. An olfactory reference syndromemonosymptomatic hypochondriasis. J Clin Psychiatry 1980; 41:57-59.

8. Munro A. Monosymptomatic hypocondriacal psychosis. Br J Psychiatry 1988; 153:37-40.

9. Suzuki K, Takei N, Iwata Y, Sekine Y, Toyoda T, Nikamura K, et al. Do olfactory reference syndrome and jiko-shu-kyofu (a subtype of taijinkyofu) share a common entity? Acta Psychiatr Scand 2004; 109:150-155.

10. Phillips KA, Gunderson C, Gruber U, Castle DJ. Delusions of body malodour: the olfactory reference syndrome. W Brewer, D Castle, D Pantelis (Eds.), Olfaction and the Brain, New York: Cambridge University Press, 2006, p.334-353.

11. Sutton. Bromidrosiphobia. JAMA 1919; 72:1267- 1268.

12. Litter CM. Pimozide for delusions of bromosis. J Am Acad Dermatol 1986; 6:1303-1304.

13. APA. Diagnostic and Statistical Manual of Mental Disorders, 5th ed., (DSM-5), Washington: APP, 2013.

14. Lochner C, Stein DJ. Olfactory reference syndrome: diagnostic criteria and differential diagnosis. J Postgrad Med 2003; 49:328-331.

15. Feusner JD, Phillips KA, Stein DJ. Olfactory reference syndrome: issues for DSM-5. Depress Anxiety 2010; 27:592-599.

16. Jenike MA. Obsessive-compulsive related disorders: a hidden epidemic. N Engl J Med 1989; 321:539-541.

17. Stein DJ, Hollander E. The spectrum of obsessive-compulsive related disorders. E Hollander (Ed.), Obsessive-Compulsive Related Disorders, Washington: American Psychiatric Press, 1993, p.241-271.

18. Bizamcer AN, Dubin WR, Hayburn B. Olfactory reference syndrome. Psychosomatics 2008; 49:77-81.

19. McElroy SL, Phillips KA, Keck PE Jr, Hudson JI, Pope HG Jr. Body dysmorphic disorder: Does it have a psychotic subtype? J Clin Psychiatry 1993; 54:389-395.

20. Fallon BA, Javitch J, Liebowitz MR. Hypochondriasis and obsessive compulsive disorders: overlaps in diagnosis and treatment. J Clin Psychiatry 1991; 52:457-460.

21. Toone BK. Psychomotor seizures, arterio-venous malformation and the olfactory reference syndrome: A case report. Acta Psychiatr Scand 1978; 58:61-66.

22. Atmaca M, Korkmaz S, Namlı MN, Korkmaz H, Kuloğlu M. Ketiyapin ile tedavi edilen olfaktör referans sendromlu bir olgu sunumu. Klinik Psikofarmakoloji Bülteni, 2011; 21:246-248.

23. Pusuroğlu M, Kandemir G, Hocaoğlu C. Ergende olfaktör referans sendromu: Bir olgu sunumu. J Mood Disord 2014; 4:41-43.