Serum pankreatik elastaz-1, acil servislerde akut pankreatit tanısı için güvenilir bir yöntem olabilir mi?

Giriş ve amaç: Acil servise karın ağrısı ile başvuran hastaların bir kısmında, rutin radyolojik ve laboratuvar testleri ile akut pankreatit teşhis edilememektedir. Bu çalışmada, akut pankreatit tanısında serum elastazın duyarlılığı araştırılmıştır. Gereç ve yöntem: Acil servise karın ağrısı ile başvuran, tanı almadan önce karın ağrısı kendiliğinden iyileşen, aynı zamanda radyolojik ve laboratuvar bulguları normal olan 80 hastanın serum elastaz düzeyine bakılmıştır. Bulgular: Laboratuvar sonuçları ve USG bulguları normal olan 2 olguda, elastaz düzeyi yüksek bulunmuştur. Bu olgular daha sonra pankreatit bulguları göstermiş ve hastaneye yatırılmıştır. Sonuç: Serum pankreatik elastaz, acil serviste akut pankreatit tanısında diğer laboratuvar testlerinden daha özgül ve duyarlı olabilir.

Can serum pancreatic elastase-1 be safe method for acute pancreatitis in emergency department?

Background/aim: Some patients admitted to the Emergency Department (ED) for abdominal pain secondary to acute pancreatitis cannot be diagnosed with routine radiologic and laboratory tests. We investigated the sensitivity of serum elastase in diagnosing acute pancreatitis. Materials and methods: We investigated serum elastase levels in 80 patients that were admitted to the ED with abdominal pain that resolved spontaneously before a diagnosis could be made and who also had normal radiological and laboratory findings. Results: Two cases had elevated elastase levels with normal USG and laboratory results. These cases later showed signs of pancreatitis and were hospitalized. Conclusion: Serum pancreatic elastase can be more sensitive and specific than the other laboratory tests for acute pancreatitis in the ED.

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Akademik Gastroenteroloji Dergisi-Cover
  • ISSN: 1303-6629
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2002
  • Yayıncı: Jülide Gülay Özler
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