Patognomonik CA 19-9 yüksekliğine sebep olan dalak kisti olgusu

CA 19-9 safra kanalı, kolon, mide, over, hepatosellüler, özofagus ve pankreas kanserleri gibi malign durumlarda yüksek seviyelerde görülebilen bir tümör göstergesidir. Pankreas kanseri ayırıcı tanısı ve yine pankreas kanserinde tedaviye cevap ve nüksün değerlendirilmesinde kullanılır. Yüksek seviyeler safra yolu obstrüksiyonu, kolanjit, inflamatuvar barsak hastalığı, akut veya kronik pankreatit, karaciğer sirozu, kistik fibrozis ve tiroid hastalıkları gibi benign durumlarda da görülebilir. CA 19- yüksekliği ile birlikte olan nadir bir durum da dalak kistleridir. Olgumuz nadir olması ve CA 19-9‘un yayınlanılan benzer olgulardan yüksek seviyelerde olması sebebiyle sunulmuştur.
Anahtar Kelimeler:

CA 19-9, pankreas, splenik kist

Splenic cyst causing high levels of pathognomonic CA 19-9: A case report

Cancer antigen 19-9 is a tumor marker present at high levels in the bile duct, colorectal, gastric, and hepatocellular cancer than esophagus or pancreas cancer. It is used to confirm the diagnosis of pancreas cancer, to assess the clinical response to the treatment, and to evaluate the recurrence of pancreatic cancer. High levels can also be seen in benign conditions, such as biliary tract obstruction, cholangitis, inflammatory bowel disease, acute or chronic pancreatitis, liver cirrhosis, cystic fibrosis, or thyroid diseases. Another rare condition which is associated with the high level of cancer antigen 19-9 is the splenic cyst. Hence, we are submitting this case report of splenic cyst because of its rareness and similarities to previously published cases with high levels of cancer antigen 19-9.

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