Vedat GÖRAL, Bülent ÖZDAL, Abdurrahman KAPLAN, DEDE ŞİT, Ramazan DANIŞ

Diyarbakır ilinde Helikobacter pilori antikor prevalansı

Giriş ve amaç: Helikobakter pilori (Hp) infeksiyonu, dünyadaki en yaygın enfeksiyon olup, ülkemiz yapılan çalışmalara göre, Helikobakter pilori infeksiyon sıklığı açısından riskli ülkeler arasında yer almaktadır. Bu çalışmayı yapmaktaki amacımız, son 10 yılda özellikle bölgemizde Hp sıklığı açısından bir değişiklik olup olmadığını araştırmaktır. Gereç ve yöntem: Çalışmaya, 0-30 yaş arası 267 asemptomatik kişi alındı. Hp'ye karşı oluşmuş IgG anti-Hp antikorlar ELISA yöntemiyle ölçüldü. Bulgular: Çalışma grubunda Hp antikor sıklığı; 0-5 yaş arası % 22.6, 6-10 yaş arası % 28.6, 11-15 yaş arası % 40.8, 16-20 yaş arası % 50, 21-30 yaş arası % 60.4 olarak saptandı. 0-30 yaş grubunda ise Hp antikor sıklığı %46.4 idi. Erkek ve kadınlar arasında prevalans farkı saptanmadı. Sonuç: 10 yıl öncesine göre bölgemizde Hp seroprevalansı azalmıştır (p

Anahtar Kelimeler:

Türkiye, İmmünglobulin G, Helicobacter pylori, Yaygınlık

The prevalance of Helicobacter pylori in the Diyarbakır city

Background/aim: Helicobacter pylori infection is the most widespread infection in the world. Our country has Hp infection risk in developing countries according to Hp infection frequency studies. In this study, our aim was to investigate whether or not there has been a variation in frequency of antibody response in our region. Materials and methods: 267 asymptomatic persons aged between 0-30 were included in the study. IgG anti Hp antibodies were measured by ELISA method. Results: Antibody frequency in our study group was 22.6% between ages 0 and 5, 28.6% between ages 6 and 10,40.8% between ages 11-15, 50% between ages 16-20, and 60.4% between ages 21-30. The total Hp antibody prevalence was 46.4% in the study group. According to these results, Hp se-roprevalence decreased significantly when compared to the results from 10 years previously (p<0.05). Conclusion: Hp prevalence has decreased over the past 10 years (p<0.5). We think these results can be attributed to improvement in socioeconomical factors and sanitation, some enviro-mental factors and widespread application of Hp eradication treatment.

Keywords:

Turkey, Immunoglobulin G, Helicobacter pylori, Prevalence,

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