Akut mezenter iskemisi, pulmoner tromboemboli ve derin ven trombozu ile komplike olan ülseratif kolit olgusu
Ülseratif kolit inflamatuvar bir barsak hastalığıdır. Kanlı diyare, karın ağrısı, kilo kaybı gibi intestinal bulguların dışında, çeşitli ekstraintestinal komplikasyonlar klinik tabloya eşlik edebilir. Tromboembolik hadiseler ülseratif kolite eşlik edebilen nadir ekstraintestinal komplikasyonlardı r. Biz daha önceden ülseratif kolit tanısı olan, klinik tablosu akut mezenter iskemisi, pulmoner tromboemboli ve derin ven trombozu ile komplike olan bir olgu sunacağız.
A case of ulcerative colitis complicated with acute mesenteric ischemia, deep vein thrombosis, and pulmonary thromboembolism
Ulcerative colitis is an inflammatory bowel disease. In addition to intestinal symptoms such as bloody diarrhea, abdominal pain, and weight loss, various extraintestinal complications may be encountered. Thromboembolic events rarely complicate ulcerative colitis. Herein, we present a case of established ulcerative colitis, which was complicated with acute mesenteric ischemia, deep vein thrombosis, and pulmonary thromboembolism
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- Bernstein CN, Blanchard JF, Houston DS, Wajda A.. The incidence of deep venous thrombosis and pulmonary embolism among patients with inflammatory bowel disease: a population-based cohort study. Thromb Haemost 2001;85:430-4.
- Bernstein CN, Wajda A, Blanchard JF. The incidence of arterial thromboembolic diseases in inflammatory bowel disease: A population-based study. Clin Gastroenterol Hepatol 2008;6:41-5.
- Danese S, Papa A, Saibeni S, et al. Inflammation and coagulation in inflammatory bowel disease: The clot thickens. Am J Gastroenterol 2007;102:174-86.
- Guédon C, Le Cam-Duchez V, Lalaude O, et al. Prothrombotic inherited abnormalities other than factor V Leiden mutation do not play a role in venous thrombosis in inflammatory bowel disease. Am J Gastroenterol 2001;96:1448-54.
- Aichbichler BW, Petritsch W, Reicht GA, et al. Anti-cardiolipin antibodies in patients with inflammatory bowel disease. Dig Dis Sci 1999;44:852-6.
- Törüner M, Erkan O, Soykan I, et al. Factor V Leiden, prothrombin G20210A and MTHFR gene mutations in inflammatory bowel disease. Turk J Gastroenterol 2004;15:250-2.
- Yasa MH, Bolaman Z, Yukselen V, et al. Factor V Leiden G1691A, prothrombin G20210A, and MTHFR C677T mutations in Turkish inflammatory bowel disease patients. Hepatogastroenterology 2007;54:1438-42.
- Hatoum OA, Spinelli KS, Abu-Hajir M, et al. Mesenteric venous thrombosis in inflammatory bowel disease. J Clin Gastroenterol 2005;39:27-31.
- Jackson CS, Fryer J, Danese S, et al. Mesenteric vascular thromboembolism in inflammatory bowel disease: a single center experience. J Gastrointest Surg 2011;15:97-100.