Biyocoğrafik Soy Tahmini ve Adli Bilimlerde Kullanımı

Adli bilimlerde SNP (Single nucleotide polymorphism, tek nükleotid polimorfizm) markırları kim-liklendirmede, fenotip belirlemede, nesep ve soy tayininde kullanılmaktadır. Biyocoğrafik soy tahminin-de farklı coğrafik bölgelerde bulunan popülasyonlar arasındaki farklılıkları gösteren soy SNP markırları (AISNPs, Ancestry Informative SNP Markers) kullanılmaktadır. AISNP markırları ile bir kişinin biyo-coğrafik orijini ve her biyocoğrafik bölgeden alınan genetik soy yüzdesi tespit edilebilir. Bu bilgiler adli bilimlerde bilinmeyen bir şüphelinin, felaket kurbanlarının veya kayıp kişilerin kimliklendirilmesinde kullanılabilir. Bu makalede biyocoğrafik soy kavramı, biyocoğrafik soy tahmininde kullanılan AISNPs panelleri, uygulama yöntemleri, kullanılan istatistiksel yöntemler ve güncel adli uygulamalar tartışıl-mıştır.

Inferring Biogeographic Ancestry and Its Use in Forensic Sciences

Even though the Forensic Psychiatry is currently defined as a sub-specialty of psychiatry in many countries, current regulations in Turkey does not provide such structured training. In this study, we aimed to evaluate the level of the knowledge of current registered mental health physicians practicing in our country, about forensic psychiatry and determine their point of view regarding forensic psychiatry to be a sub-specialty.In forensic applications SNP (Single nucleotide polymorphism) markers are used for identification, determination of phenotypes, lineage and ancestry. Ancestry informative SNP markers (AISNPs), which show differences between populations in different geographic regions, are used for estimating of the bio-geographic ancestry. The biogeographical origin of a person and the percentage of genetic lineage taken from each biogeographic region can be determined using AISNP markers. This information may assist forensic investigations of unknown contributors or identification of missing persons and disaster victims. In this review, biogeographic ancestry concept, AISNPs panels used in estimation of the biogeographic ancestry, application methods, statistical methods, and current forensic applications has been discussed.

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