Aydın GÜREL, Damla HAKTANIR, İbrahim KURBAN, Sevde İSLAMOĞLU, Serhat ÖZSOY

A Case of Sebaceous Carcinoma Detected on the Eyelid of a Horse

This article describes a case of sebaceous carcinoma located on the right lower eyelid of an 11-year-old female Haflinger horse and its surgical, clinical, and histopathological aspects. The Haflinger horse was referred to the clinics of the Department of Surgery with a complaint of a swelling on the right lower eyelid, which had been present for 1 year and began to grow during the past few months. A clinical inspection revealed a soft, multinodular tumoral mass, with the dimensions of 4×5 cm, located in the inferior region of the right lower eyelid and protruding outward. The surgical removal of the mass was decided after the clinical inspection. The excised tumoral mass was submitted to the department of pathology for histopathological evaluation, which revealed well-circumscribed multilobular structures comprising foci of round-to-ovoid and polygonal pleomorphic neoplastic epithelial cells with prominent nuclei and eosinophilic cytoplasm separated by bands of the fibrous tissue of varying thickness. There was prominent cellular pleomorphism; some cells contained cytoplasmic vacuoles of various sizes, whereas some exhibited sebaceous differentiation. Based on these histopathological findings, sebaceous carcinoma of the sebocyte type was diagnosed.

PDF

___

Arıkan N., Özer, K., Gürel, A., Gülanber, E.G., Yeşildere T., 1997. İki Atta karşılaşılan Konjunktival Tümör Olgusu. Veteriner Cerrahi Dergisi 3(2), 5658.

Banks, W.J., 1986. Comparative Organology In Applied Veterinary Histology, Second Edition; pp.543 - 544, Williams and Wilkins, Baltimore, London.

Baker, J.R., Leyland, A., 1975. Histolojik survey of tumours of the horse, with particular reference to those of the skin. Veterinary Record 96, 419-422. [CrossRef]

Baptiste, K.E., Grahan, B.H., 2000. Equin orbital neoplasia; a review of 10 cases (1983- 1998). Canadian Veterinary Journal 41, 291-295.

Brooks, D.E., 1999. Equin Ophthalmology In Veterinary Ophtholmology (Gelatt K.N. ed.) 3rd Ed. pp.1053-1116.

Choi, S.K., Park, J.K., Jeon, W.B., Lee, K.H., Cho, G.J., 2013. Meibomian Epithelioma of The Lower Eyelid in a Thoroughbred Horse. Pakistan Veterinary Journal 2(33), 244-247.

Cotchin, E., 1977. A general Survey of Tumours in the Horse. Equin Veterinary Journal Vol: 9No; 1, 16-21.

Giulino, E.A., 2011. Equin Adnexal and nasolacrimal disase In ; Equin Ophtalmology pp. 133-180,.Ed. B.C. Gilger, Elsevier Saunders, Maryland, Heights. [CrossRef]

Goldschmidt, M.H., Goldschmidt, K.H., 2017. Epithelial and Melanocytic Tumors of the Skin. In Tumors in Domestic Anbimals (Meuten D.J. ed.) Fifty Edi. pp. 108-111. Wiley Black well.

Gross T.L., Iherke, P.J., Walder, E.J. Affolter, V.K., 2015. Skin disases of the dog and cat, clinical and histopathologic diagnosis, second editions, pp. 650-654. BlackWell Publishing Company. Oxford, London.

Knottenbelt, D.C., 2011. Ocular, Orbital and Periorbital NeoplasticConditions of the Horse. Available from: http://www.equineophtho. org/uploads/documents/KnottenbeltNotes2.pdf.

Lavach, J.D., Severin G.A., 1977. Tumours of the equin eyes, adnexa and orbit; a review 68 cases. Journal of the American Veterinary Medical Associations 170, 202-206.

Montgomery, K.M., 2014. Equin Ocular neoplasia. A review, Equin Veterinary Educations 26(7), 372-380. [CrossRef]

Rachel, L.M., Karen Paige, C., John, P., Philip, A.M., 2011. Primary Lacrimal gland adenocarsinoma of the third eyelid in a horse. Veterinary Oftalmology 14(1), 48-54.

Rooney, J.R., Robertson J.L., 1996. Ocular and Adnexal Neoplasia In; Equin Ophthalmology, pp. 130-131. Iowa State University Press, Ames-Iowa.