Bifosfonatlar ve çenelerde görülen osteonekroz

Bifosfonatlar günümüzde kemik metabolizması ile ilgili pek çok hastalığın tedavisinde yaygın olarak kullanılmaktadır. Bifosfonatların yüksek dozda intravenöz uygulamaları nedeni ile ilaca bağlı bir yan etki olarak çenelerde osteonekroz oluşabilmektedir. Lezyonlar kendiliğinden oluşabildiği gibi bir enfeksiyon ve diş çekimi genellikle olayı hızlandırmaktadır. Bu nedenle diş hekimleri bifosfonat kullanan hastaların tedavisinde dikkatli olmalıdırlar.

Anahtar Kelimeler:

Bifosfonat, Çene, Osteonekroz

Bisphosphonates and osteonecrosis of the jaws

Bisphosphonates are widely used for treatment of many bone metabolism related disease. Intravenous administration of high doses of bisphosphonates for the management of benign conditions occasionally lead to development of osteonecrosis of the jaws. In many cases lesions appear spontaneously or following an infection or a tooth extraction. Dentists should be cautious in the treatment of patients using bisphosphonates.

Keywords:

Bisphosphonate, Jaw, Osteonecrosis,

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