Gökhan Alıcı, Gökmen Bellur, Birol Özkan, Mustafa Bulut, Müslüm Şahin, Bilal Boztosun, Ali Metin Esen

Kardiyak Sendrom X Hastalarında Etiyolojik Bir Faktör Olarak İskeminin Araştırılmasında QT Dispersiyonu Ölçümü

Amaç: Pozitif egzersiz testi ile birlikte angina ya da angina benzeri göğüs ağrısı ve normal koroner anjiografi ile karakterize kardiyak sendrom X'in (KSX) gerçek nedeni tartışmalıdır. QT dispersiyonu (QTd) ölçümü miyokard heterojenitesini gösteren invazif olmayan bir yöntemdir. İskemik miyokardın iskemik olmayan miyokardla repolarizasyon süresi farkı QTd'de uzamaya yol açar. Bu çalışmanın amacı KSX'li hastalarda QTd ölçümü ile etyolojik bir faktör olarak iskemi varlığının araştırılmasıdır. Yöntem: Stabil angina pektorisi olan 105 hasta çalışmaya dahil edildi. Toplam 105 hastanın 66'sı (38 kadın, 28 erkek, ortalama yaş: 48,08±10,21) pozitif egzersiz testi ve normal koroner anjiografi ile KSX olarak teşhis edildi. 39 hastadan oluşan kontrol grubu (24 kadın, 15 erkek, ortalama yaş: 50,84±11,34) ise negatif egzersiz testi ve normal koroner anjiografiye sahipti. QT intervali istirahat ve zirve egzersiz sırasında alınan standart 12 derivasyonlu elektrokardiyografi üzerinden ölçüldü. QTd maksimum

Anahtar Kelimeler:

Kardiyak sendrom X, QT dispersiyonu, iskemi, egzersiz treadmill testi.

Measurement of The QT Dispersion In Patients With Cardiac Syndrome X For The Investigation of Ischemia As An Etiological Factor

Clinical and demographic characteristics of the groups such as age, gender body mass index, systolic and diastolic blood pressure showed no statistically significant differences between both groups. Although there was no difference in QTd values between groups at baseline (43,28 ± 12,55 msec in the positive ETT group, and 40,28 ± 11,08 msec in the control group, p=NS), peak exercise QTd was much higher in the positive ETT group than the control group (57,40 ± 13,70 msec and 28,23 ± 5,05 msec, respectively, p< 0.01). Since QTd greater than 60 msec related to ischemia has been previously reported, ETT positive patients were reevaluated in two different subgroups with QTd ? 60 msec (34 patients), and QTd < 60 msec(32 patients). The sum of ST depression were much more in the QTd ? 60 msec group (7,22 ± 0,74 vs 4,40 ± 1,78; t: -8,458, p

Keywords:

Cardiac syndrome X, QT dispersion, ischemia, exercise treadmill testing.,

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ISSN: 2149-2972
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 1990
Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi