Doğumsal Kardiyak Şantlarla Bağlantılı Pulmoner Arteriyel Hipertansiyonda Tedavi Yaklaşımları: Kardiyoloji ve Kalp-Damar Cerrahisinde Önemli Bir Yoğun Bakım Hasta Grubu
hipertansiyonda kombinasyon tedavisiyle ilgili yapılan ça- lışmalardan elde edilen veriler çelişkilidir. Bazı çalışmalar- da bosentan tedavisine sildenafi l eklenmesi hemodinamik özellikleri ve egzersiz kapasitesini artırırken; bazı çalışma- larda kombinasyon tedavisi etkisiz bulunmuştur(23). Fakat yine de doğumsal kalp hastalığıyla ilişkili pulmoner arte- riyel hipertansiyon hastalarının, pulmoner arteriyel hiper- tansiyon spesifi k tedaviden fayda gördüğü gösterilmiştir. Ortalama dört yıl takip edilen toplam 229 Eisenmenger sendromlu hastada yapılan retrospektif bir çalışmada pul- moner arteriyel hipertansiyon spesifi k tedavi gören grupta, tedavi almayan gruba göre daha düşük ölüm oranı saptan- mıştır(24)
Treatment Strategies of Pulmonary Arterial Hypertension Associated with Congenital Heart Defects with Shunt: A Group of Important Intensive Care Patient in Cardiology and Cardiovascular Surgery
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