Banu YUCEL, Huseyin SAHIN, Oktay YILDIZ, Sevgi KOLAYLI

Apilarnilin Biyoaktif Bileşenleri ve Etki Mekanizması

Amaç: Apilarnil, erkek arı larvalarından üretilen doğal bir arı ürünüdür. Hem insan hem de hayvanlar için oldukça faydalı özelliklere sahiptir. Erkek arı larvalarının kimyasal bileşimi, mineral tuzlar, vitaminler, karbohidratlar, lipitler ve amino asitlerden meydana gelmektedir. Bu larvaların genital fonksiyonun temel ölçümleri üzerinde doğrudan etkisi olan biyo-uyarıcı hipotalamus-hipofiz-adrenal aks fonksiyonu üzerinde etkisi vardır. Mevcut çalışma, apilarnilin detaylı fizikokimyasal karakterizasyonunu ortaya çıkarmak ortaya çıkarmak adına tasarlanmıştır. Materyal ve Metot: Bu çalışmada, Türkiye'den taze hasat edilmiş apilarnil örneği, bazı fizikokimyasal parametrelerin yüzdesi (nem, kül, toplam lipit, toplam protein ve kolesterol), bazı hormonların seviyesi (östradiol, prolaktin, progesteron ve testosteron) ve bazı yağ asitlerinin karakterizasyonu açısından incelenmiştir.Bulgular: Edinilen sonuçlara göre; testosteron ve progesteron sırasıyla 14.80 ± 0.05 ng/g ve 14.40±0.05 ng/g olarak yüksek düzeyde ölçüldü ve ayrıca konjuge linoleik asit (%52.62) gaz kromatografisi ile ana yağ asidi bileşeni olarak tanımlandı. Sonuç: Değerlendirme sonuçları, apilarnilin, yüksek seviyeli biyolojik özelliklerinden dolayı kayda değer bir doğal kaynak olarak görülebileceği sonucunu ortaya koymuştur.

Anahtar Kelimeler:

Bal arısı, erkek arı larvası, streoid hormon, testosteron, yağ asidi

Bioactive Components and Effect Mechanism of Apilarnil

Objective: Apilarnil is a natural bee product produced from the drone larvae. It has highly beneficial properties for both humans and animals. The chemical composition of the drone larvae consists of mineral salts, vitamins, carbohydrates, lipids, and amino acids. It has an influence on the function bio-stimulating hypothalamic–pituitary–adrenal axis has a direct impact on the essential measures of the genitalia function. The obtaining study was performed to reveal the detail physico-chemical characterization of apilarnil. Material and Methods: In this study, a freshly harvested apilarnil sample from Turkey was investigated in terms of the percentage of some physicochemical parameters (moisture, ash, total lipid, total protein, and cholesterol), the level of some hormones (estradiol, prolactin, progesterone, and testosterone), and the characterization of some fatty acids.Results: According to the existing results; testosterone and progesterone were noted highly level as 14.80±0.05 ng/g and 14.40±0.05 ng/g, respectively, moreover, conjugated linoleic acid (52.62%) was defined as a marker of fatty acid by gas chromatography. Conclusion: The evaluating results showed that apilarnil could be seen as a remarkable natural source thanks to its high-level bio-properties.

Keywords:

Honey bee, drone bee larvae, steroid hormone, testosterone, fatty acid,

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