Gökçe TURAN, Berna ASLAN ÇETİN, Gözde DEMİREZEN, Nurullah PEKER

Tubal Ektopik Gebelik Tanısında Tam Kan Sayımı Parametrelerinin Değerlendirilmesi

Amaç: Bu çalışmadaki amaç ektopik gebeliği (EG) olan hastalar ile sağlıklı intrauterin gebeliği olan hastaların hemogram parametrelerini karşılaştırmaktır.Materyal ve Metod: Ocak 2013 ile Ocak 2017 tarihleri arasında tersiyer bir merkezde tubal EG tanısı konan hastalar ile ilk trimester intrauterin gebeliği olan hastaların demografik verileri ve tam kan sayımındaki beyaz küre (WBC), hemoglobin (Hgb), hematokrit (Hct), nötrofil, lenfosit, platelet (PLT), ortalama platelet hacmi (MPV), nötrofil-lenfosit oranı (NLO) ve platelet-lenfosit oranı (PLO) karşılaştırıldı.Bulgular: EG’i olan 718 hasta ile sağlıklı intrauterin gebeliği olan 937 hasta çalışmaya dahil edildi. Yaş, gravida, parite ve abortus EG grubunda (çalışma grubu) anlamlı olarak daha yüksek izlenirken (p<0,001), gestasyonel hafta ise kontrol grubunda anlamlı olarak yüksek bulundu (p<0,001). Hgb, Hct ve MPV değerleri kontrol grubunda anlamlı olarak yüksek izlenirken (p<0,001), WBC, PLT, NLO ve PLO değerleri karşılaştırıldığında iki grup arasında anlamlı fark izlenmedi.Sonuç: Sonuç olarak EG’i öngörmede hemogram parametrelerinden sadece MPV değeri anlamlı bulundu. Bu çalışmada NLO ve PLO değerleri EG tanısında anlamlı bulunmadı. EG tanı ve tedavi protokollerinde hemogram, NLO ve PLO değerleri daha olası ilişkileri araştırmak için daha geniş hasta gruplarının inceleneceği prospektif çalışmalara ihtiyaç vardır.

Anahtar Kelimeler:

Ektopik gebelik, Mean platelet volume, Nötrofil-lenfosit oranı, Platelet-lenfosit oranı

Evaluation of Complete Blood Count Parameters in Tubal Ectopic Pregnancy

Background: The aim of this study was to compare the hemogram parameters of patients with ectopic pregnancy (EP) and healthy intrauterine pregnancy.Materials and Methods: Between January 2013 and January 2017, the demographic data of patients with first-trimester intrauterine pregnancy and patients with a diagnosis of tubal EP issue in a tertiary center, and white blood cell count (WBC), hemoglobin (Hgb), hematocrit (Hct), neutrophil and lymphocyte count, neutrophil-lymphocyte ratio (NLR), platelet count (PLT), platelet lymphocyte ratio (PLR) and mean platelet volume (MPV) values on complete blood count were recorded and compared with each other.Results: A total of 718 patients with ectopic pregnancies and 937 patients with healthy intrauterine pregnancies were included in the present study. Between groups, age, gravida, parity, and abortion in the group with EP (study group) were monitored significantly higher (p <0.001), the gestational week was found significantly higher in the control group (p <0.001). Hgb, Hct and MPV values of the groups were monitored significantly higher in the Control Group (p<0.001), and no significant differences were detected between the WBC, PLT, NLR and PLR values of both groups.Conclusions: As a result, only the MPV value was found significant among the hemogram parameters in predicting ectopic pregnancy. In this study, NLR and PLR values were not found significant in the diagnosis of EP. Prospective studies with larger participants are needed to investigate more possible relationships with hemogram, NLR and PLR values in EP diagnosis and treatment protocols.

Keywords:

Ectopic pregnancy, Mean platelet volume, Neutrophil-lymphocyte ratio, Platelet-lymphocyte ratio,

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