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Patient safety necessitates building the systems which prevent the errors that may emerge during healthcare services from occurring in such a way to harm patients and taking necessary measures. For this reason, one of the most significant duties of the hospital management is to establish and develop patient safety. Throughout patient safety, a major part of patient care and medical activities is conducted by nurses. Therefore, this study was performed with the intent of evaluating nurses’ perception of management’s patient safety practices on the grounds that both the number of nurses is high and nurses are a member of the healthcare staff that is object of the patient most. The population of the research comprised of 355 nurses serving at Bulent Ecevit University Practice and Research Hospital. In collecting data, questionnaire forms were used. Factor analysis, ANOVA and t-test were exploited in the statistical analysis of the data. As a result of the conducted statistical analyses, it was found that the management has to lay emphasis on supply factor in terms of patient factor.