Erdem FADILOĞLU, Canan UNAL, Atakan TANACAN, M.sinan BEKSAC

Romatoid artrit hastalarının gebelik sonuçları

Amaç: Bu çalışmanın amacı romatoid Artrit (RA) hastalarının gebelik sonuçlarını değerlendirmektir. Gereç ve Yöntem: Retrospektif planlanan çalışmamız 39 hastadan oluşmaktadır. Hastalar seropozitivite, hastalık süresinin 5 yıldan uzun olması ve ilaç kullanımı açısından değerlendirildiler. Bulgular: Preterm doğum ve intrauterin gelişme geriliği oranı sırasıyla 33.3% ve 21.2% olarak bulundu. Seropozitif ve seronegatif hastalara ilişkin yapılan karşılaştırmalarda anlamlı fark izlenmedi. Hastalığın 5 yıldan uzun süredir olması ya da olmamasının da gebelik sonuçlarına etki etmediği görüldü. Ek bir hastalığı olanlarda ise diğer hastalarda benzer oranda düşük izlendi (%16.6, %14.8). İlaçsız olarak izlenen hastalarda ise istatistiksel farklılık olmamasına rağmen daha yüksek oranda düşük izlendi. Sonuç: RA tanısı olan gebeliklerin preterm doğum ya da intrauterin gelişme geriliği gibi komplikasyonların daha sık izlenmesi nedeniyle yüksek riskli gebelikler olarak değerlendirilmesi gerekmektedir.

Anahtar Kelimeler:

romatoid artrit, gebelik, obstetrik sonuç, düşük, preterm doğum, intrauterin gelişme geriliği, seropozitivite

Pregnancy outcomes of patients with rheumatoid arthritis

Purpose: The aim of this studywas to evaluate the obstetric outcomes of women with rheumatoid arthritis (RA) Materials and Methods: This retrospective study consisted of 39 women with RA. Patients were evaluated in terms of seropositivity, having disease >5 years or not and use of any medication. Results: Rate of preterm delivery and intrauterine growth retardation was 33.3% and 21.2%, respectively. Comparisons between seropositive and seronegative women did not show any significant difference. Having disease more or less than 5 years did not show any significant difference in terms of obstetric outcomes. Women with a coexisting disease had a similar rate of miscarriage rate compared to remainders (16.6% vs 14.8%). Women followed up without any medication has also higher rates of miscarriage despite lack of statistical significance. Conclusion: Pregnancies of women with RA must be considered as high risk due to increased rates of adverse pregnancy outcomes such as preterm delivery and intrauterine growth retardation.

Keywords:

Pregnancy, rheumatoid arthritis, obstetric outcome, miscarriage, preterm delivery, intrauterine growth retardation, seropositivity,

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