Murat Memiş, Gülhan Kurtoğlu Çelik, Alp Şener, Havva Şahin Kavaklı, Ferhat İçme, Onur Karakayalı, Halil Yıldırım

Pulmoner tromboemboli hastalarında ortalama trombosit hacmindeki değişiklikler

Amaç: Bu klinik çalışmada amaç pulmoner tromboemboli tanısı alan hastalarda ortalama trombosit hacmi ile emboli yükünün ilişkisini ortaya koymaktır.Gereç ve Yöntem: Bu retrospektif çalışmaya pulmoner emboli tanısı alan 120 hasta dahil edildi. Hastaların ortalama trombosit hacmi, Troponin-I, D-dimer değerleri, arter kan gazları, göğüs radyografisi, elektrokardiyografi, ekokardiyografi ve venöz doppler ultrason bulguları kaydedildi. Ayrıca bilgisayarlı tomografi anjiyografi kullanılarak pulmoner arteriyel obstrüksiyon indeksi hesaplandı.Bulgular: Ortalama trombosit hacmi ile pulmoner arter basıncı arasında ve pulmoner arteriyel obstrüksiyon indeksi arasında pozitif korelasyon tespit edildi. Ortalama trombosit hacmi < 8.5fl olan ve > 8.5fl olan gruplar arasında pulmoner arter obstrüksiyon indeksi açısından istatistiksel anlamlı bir fark tespit edildi (25.0 and 45.0). Ortalama trombosit hacmi > 8.5fl olan olan grupta pulmoner arter basıncı < 8.5fl olan gruptan istatistiksel anlamlı olarak yüksek bulundu.Sonuç: Pulmoner arteriyel bilgisayarlı tomografi obstrüksiyon indeksi ile ortalama trombosit hacmi arasındaki korelasyonun pulmoner embolizm şiddetini belirlemedeki değeri net değildir.

Anahtar Kelimeler:

Pulmonary embolism, mean platelet volume

Changes in mean platelet volume values in patients with pulmonary thromboembolism

Purpose: This clinical study aimed at determining whether mean platelet volume values were useful in predicting embolic load by comparing the values of patients diagnosed with pulmonary thromboembolism with pulmonary arterial computed tomography obstruction index.Material and Methods: This retrospective study enrolled 120 inpatients with pulmonary thromboembolism diagnosis in emergency service. Patients’ mean platelet volume, Troponin-I, D-dimer values, arterial blood gases, chest radiographs, electrocardiograms, echocardiograms and venous doppler ultrasound findings were recorded. Moreover, pulmonary arterial computed tomography obstruction index for each case was calculated by extracting data from patients’ computed tomography angiographies.Results: There was a statistically significant difference particularly between pulmonary arterial computed tomography obstruction index values of the cases having mean platelet volume value < 8.5fl and mean platelet volume value > 8.5fl (25.0 and 45.0). Pulmonary arterial pressure of the group with mean platelet volume level > 8.5 was found significantly higher compared to the group with mean platelet volume level < 8.5fl.Conclusions: Usefulness of correlation between mean platelet volume and pulmonary arterial computed tomography obstruction index in assessing the severity of embolism is unclear.

Keywords:

Pulmoner embolizm, ortalama trombosit hacmi,

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