Bahriye ATMIŞ, Aysun KARABAY BAYAZIT, Engin MELEK, Çağla ÇAĞLI, Ali ANARAT

Post-enfeksiyöz glomerülonefrit sıklığı: tek merkez bulguları

Amaç: Bu çalışmanın amacı Çukurova Üniversitesi Tıp Fakültesi Çocuk Nefroloji Bilim Dalında Kasım-Aralık 2016 aylarında başvuran hastalarda post-enfeksiyöz glomerülonefrit (PIGN) tanı sıklığını geriye dönük değerlendirmektir..Gereç ve Yöntem: Bu tarihlerde kliniğimize başvuran 13 PIGN’li çocuk hastanın klinik, laboratuvar sonuçları ve takiplerinin sonuçları incelenmiştir.Bulgular: Çalışamaya alınan 13 PIGN tanılı çocuğun ortalama yaşı 9 (3-15) idi. Tüm hastaların üst solunum yolu veya gastrointestinal enfeksiyon öyküsü vardı. Başvuru şikayetleri sıklık sırasına göre ödem (%70), oligüri (%38,5), makroskobik hematüri (%23), hipertansiyon (%15,3), nefes darlığı (%15,3) idi. Kompleman C3 tüm hastalarda düşük iken bir hastada C3 ve C4 düşüklüğü vardı. Aynı hastada nefrotik düzeyde proteinüri ile birlikte akut böbrek yetmezliği vardı. Bu hastaya böbrek biyopsisi yapılarak diffüz proliferatif glomerülonefrit tanısı konuldu.Sonuç: Günümüzde PIGN gelişmekte olan ülkelerde daha yüksek oranda görülmektedir. Biz de kısa bir dönem içerisinde PIGN hasta sayısında artış tespit ettik ve bu çalışma ile farklı klinik başlangıcı ve seyri olan bu hastalar için genel pediatri hekimlerinin dikkatini çekmeyi amaçladık.

Anahtar Kelimeler:

çocukluk çağı, post-enfeksiyöz glomerülonefrit, proteinüri, hipokomplemantemi

Incidence of post-infectious glomerulonephritis: single center results

Purpose: The aim of this study was to retrospectively evaluate the incidence of post-infectious glomerulonephritis (PIGN) in department of Pediatric Nephrology at Cukurova University between November-December 2016. Materials and Methods: The clinical and laboratory datas of 13 children with PIGN who were seen in our clinic between November-December 2016, and their follow-up results were evaluated retrospectively.Results: Thirteen children who diagnosed PIGN were evaluated with the mean age of 9 (3-15) years. All of the patients had history of throat or gastrointestinal infections. Symptoms of the patients at admission were edema (100%), oliguria (38.5%), macroscopic hematuria (23%), hypertension (15.3%), dispnea (15.3%), respectively. Serum complement C3 was low in all patients while one patient had both low serum complement C3 and C4. The patient who had hypocomplementemia (both C3 and C4) also had severe proteinuria and acute kidney injury. Renal biopsy was performed to this patient and diagnosed diffuse proliferative glomerulonephritis after renal biopsy.Conclusion: PIGN is observed with higher incidence in the developing countries in current era. We detected an increase in the number of PIGN patients in a short period and we aimed to draw attention of pediatricians about PIGN patients with different clinical presentations.

Keywords:

: children, post-infectious glomerulonephritis, proteinuria, hypocomplementemia,

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